L-N-Boc-homophenylalanine propylamide

Base Information

Chemical Name:L-N-Boc-homophenylalanine propylamide
CAS No.:1335290-28-2
Molecular Formula:C₁₈H₂₈N₂O₃
Molecular Weight:320.432
Hs Code.:

Synonyms:L-N-Boc-homophenylalanine propylamide

Suppliers and Price of L-N-Boc-homophenylalanine propylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of L-N-Boc-homophenylalanine propylamide

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Technology Process of L-N-Boc-homophenylalanine propylamide

There total 2 articles about L-N-Boc-homophenylalanine propylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.5%

: 107-10-8,42939-71-9
propylamine

: 1335290-25-9
DL-N-Boc-homoPhe-SEt

: 1335290-28-2
L-N-Boc-homophenylalanine propylamide

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tert-butyl alcohol; at 37 ℃; for 24h; optical yield given as %ee; Resolution of racemate; Enzymatic reaction;
DOI:10.1002/adsc.201100389

Reference yield:

: 108524-68-1
2-((tert-butoxycarbonyl)amino)-4-phenylbutanoic acid

: 1335290-28-2
L-N-Boc-homophenylalanine propylamide

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 0 - 20 °C

2: 1,8-diazabicyclo[5.4.0]undec-7-ene / tert-butyl alcohol / 24 h / 37 °C / Resolution of racemate; Enzymatic reaction

With dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene; dicyclohexyl-carbodiimide; In dichloromethane; tert-butyl alcohol;
DOI:10.1002/adsc.201100389