trans-4-[4-(4-Phenylmethanesulfonylindol-1-yl)-pyrimidin-2-yl-amino]-cyclohexanol

Base Information

Chemical Name:trans-4-[4-(4-Phenylmethanesulfonylindol-1-yl)-pyrimidin-2-yl-amino]-cyclohexanol
CAS No.:1032452-77-9
Molecular Formula:C₂₅H₂₆N₄O₃S
Molecular Weight:462.572
Hs Code.:

Synonyms:trans-4-[4-(4-Phenylmethanesulfonylindol-1-yl)-pyrimidin-2-yl-amino]-cyclohexanol

Suppliers and Price of trans-4-[4-(4-Phenylmethanesulfonylindol-1-yl)-pyrimidin-2-yl-amino]-cyclohexanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of trans-4-[4-(4-Phenylmethanesulfonylindol-1-yl)-pyrimidin-2-yl-amino]-cyclohexanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of trans-4-[4-(4-Phenylmethanesulfonylindol-1-yl)-pyrimidin-2-yl-amino]-cyclohexanol

There total 3 articles about trans-4-[4-(4-Phenylmethanesulfonylindol-1-yl)-pyrimidin-2-yl-amino]-cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 7.0%

: 1032452-76-8
trans-4-[4-(4-benzylsulfanylindol-1-yl)-pyrimidin-2-ylamino]-cyclo-hexanol

: 1032452-77-9
trans-4-[4-(4-Phenylmethanesulfonylindol-1-yl)-pyrimidin-2-yl-amino]-cyclohexanol

Guidance literature:: trans-4-[4-(4-benzylsulfanylindol-1-yl)-pyrimidin-2-ylamino]-cyclo-hexanol; With 3-chloro-benzenecarboperoxoic acid; In chloroform; at 20 ℃;

With sodium hydrogencarbonate; In chloroform; water;

Reference yield:

: 92554-48-8
4-benzylthioindole

: 1032452-77-9
trans-4-[4-(4-Phenylmethanesulfonylindol-1-yl)-pyrimidin-2-yl-amino]-cyclohexanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h / 0 °C

1.2: 20 °C

2.1: 1-methyl-pyrrolidin-2-one / 4 h / 110 °C

3.1: 3-chloro-benzenecarboperoxoic acid / chloroform / 20 °C

With sodium hydride; 3-chloro-benzenecarboperoxoic acid; In 1-methyl-pyrrolidin-2-one; chloroform; N,N-dimethyl-formamide;

Reference yield:

: 1032452-75-7
4-benzylsulfanyl-1-(2-chloro-pyrimidin-4-yl)-1H-indole

: 27489-62-9
trans-4-hydroxycyclohexylamine

: 1032452-77-9
trans-4-[4-(4-Phenylmethanesulfonylindol-1-yl)-pyrimidin-2-yl-amino]-cyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1: 1-methyl-pyrrolidin-2-one / 4 h / 110 °C

2: 3-chloro-benzenecarboperoxoic acid / chloroform / 20 °C

With 3-chloro-benzenecarboperoxoic acid; In 1-methyl-pyrrolidin-2-one; chloroform;