1-tert-butyl-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine

Base Information

• Chemical Name: 1-tert-butyl-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine
• CAS No.: 131657-49-3
• Molecular Formula: C₁₅H₂₂N₂O₂S
• Molecular Weight: 294.418
• Mol file: 131657-49-3.mol

Synonyms:1-tert-butyl-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine

Chemical Property of 1-tert-butyl-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-tert-butyl-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine

There total 1 articles about 1-tert-butyl-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N-t-butylpyrrolidone (20687-53-0) + Tosyl isocyanate (4083-64-1) → 1-tert-butyl-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine (131657-49-3)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 18h;

DOI:10.1021/jo00004a035

Reference yield:

1-tert-butyl-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine (131657-49-3) + benzaldehyde (100-52-7) → rel-(3S,1'S)-1-tert-butyl-3-(1'-hydroxybenzyl)-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine (131657-67-5,131657-68-6) + rel-(3S,1'R)-1-tert-butyl-3-(1'-hydroxybenzyl)-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine (131657-67-5,131657-68-6)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h; Yield given. Yields of byproduct given;

DOI:10.1021/jo00004a035

upstream raw materials:

N-t-butylpyrrolidone

Tosyl isocyanate

Downstream raw materials:

rel-(3S,1'S)-1-tert-butyl-3-(1'-hydroxybenzyl)-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine

rel-(3S,1'R)-1-tert-butyl-3-(1'-hydroxybenzyl)-2-(((4-methylphenyl)sulfonyl)imino)pyrrolidine