(2-Isopropoxyphenyl)methanamine

Base Information

• Chemical Name: (2-Isopropoxyphenyl)methanamine
• CAS No.: 227199-51-1
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.235
• Hs Code.: 2922299090
• European Community (EC) Number: 813-956-6
• DSSTox Substance ID: DTXSID00352874
• Wikidata: Q82130277
• ChEMBL ID: CHEMBL4540360
• Mol file: 227199-51-1.mol

Synonyms:(2-Isopropoxyphenyl)methanamine;227199-51-1;1-(2-Isopropoxyphenyl)methanamine;(2-propan-2-yloxyphenyl)methanamine;[2-(propan-2-yloxy)phenyl]methanamine;(2-Isopropoxyphenyl)methylamine;1-[2-(propan-2-yloxy)phenyl]methanamine;2-isopropoxy benzyl amine;SCHEMBL855754;CHEMBL4540360;DTXSID00352874;RJWAKPHKRZMFHG-UHFFFAOYSA-N;1-(2-Isopropoxyphenyl)methylamine;HMS1704A17;BBL011262;MFCD04037890;STK938943;AKOS000147125;PS-5964;AM20030391;CS-0216559;FT-0676934;EN300-51307;1-(2-isopropoxyphenyl)methanamine, AldrichCPR;S10925;A878461;Z57102478

Chemical Property of (2-Isopropoxyphenyl)methanamine

Chemical Property:

• Vapor Pressure: 0.0254mmHg at 25°C
• Refractive Index: 1.518
• Boiling Point: 247.6°Cat760mmHg
• Flash Point: 98.9°C
• PSA: 35.25000
• Density: 0.99g/cm³
• LogP: 2.63280
• Storage Temp.: 2-8°C
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 165.115364102
• Heavy Atom Count: 12
• Complexity: 125

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Isopropoxyphenyl)methanamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)OC1=CC=CC=C1CN

Technology Process of (2-Isopropoxyphenyl)methanamine

There total 6 articles about (2-Isopropoxyphenyl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C15H23NO3 → (2-(isopropyloxy)phenyl)methanamine (227199-51-1)

Guidance literature:

With trifluoroacetic acid; In dichloromethane;

DOI:10.1002/chem.201903066

Reference yield: 84.0%

2-isopropoxybenzonitrile (90921-35-0) → (2-(isopropyloxy)phenyl)methanamine (227199-51-1)

Guidance literature:

With potassium borohydride; In ethanol; water; at 20 - 50 ℃;

DOI:10.1021/ja1032277

Reference yield:

C10H13NO2 → (2-(isopropyloxy)phenyl)methanamine (227199-51-1)

Guidance literature:

With ammonium formate; zinc; In methanol; for 1h; Reflux;

upstream raw materials:

2-isopropoxybenzonitrile

salicylonitrile

salicylaldehyde

2-isopropoxybenzaldehyde

Downstream raw materials:

C₁₇H₁₉NO