Technology Process of C16H22N2O2
There total 6 articles about C16H22N2O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; 20% palladium hydroxide-activated charcoal; hydrogen;
In
methanol;
at 20 ℃;
for 18h;
under 760.051 Torr;
chemoselective reaction;
DOI:10.1021/ol302176z
DOI:10.1021/ol302176z
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 1 h / Inert atmosphere; Reflux
2.1: ozone; oxygen / dichloromethane; methanol / 0.42 h / -78 °C
2.2: 0.67 h / -78 - 20 °C / Inert atmosphere
2.3: 20 °C / Inert atmosphere
3.1: hydrogen; 20% palladium hydroxide-activated charcoal; hydrogenchloride / methanol / 18 h / 20 °C / 760.05 Torr
With
hydrogenchloride; Hoveyda-Grubbs catalyst second generation; 20% palladium hydroxide-activated charcoal; hydrogen; oxygen; ozone;
In
methanol; dichloromethane;
DOI:10.1021/ol302176z
DOI:10.1021/ol302176z
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 1H-imidazole / dichloromethane / Reflux; Inert atmosphere
2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
2.2: -78 - 20 °C / Inert atmosphere
3.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 1 h / Inert atmosphere; Reflux
4.1: ozone; oxygen / dichloromethane; methanol / 0.42 h / -78 °C
4.2: 0.67 h / -78 - 20 °C / Inert atmosphere
4.3: 20 °C / Inert atmosphere
5.1: hydrogen; 20% palladium hydroxide-activated charcoal; hydrogenchloride / methanol / 18 h / 20 °C / 760.05 Torr
With
1H-imidazole; hydrogenchloride; Hoveyda-Grubbs catalyst second generation; 20% palladium hydroxide-activated charcoal; hydrogen; oxygen; ozone; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ol302176z
DOI:10.1021/ol302176z
