4-[3-(Trifluoromethyl)phenyl]aniline

Base Information

Chemical Name:4-[3-(Trifluoromethyl)phenyl]aniline
CAS No.:397-28-4
Molecular Formula:C13H10 F3 N
Molecular Weight:237.224
Hs Code.:2921499090
European Community (EC) Number:673-268-5
DSSTox Substance ID:DTXSID201260069
Nikkaji Number:J1.704.557A
Mol file:397-28-4.mol

Synonyms:397-28-4;4-[3-(trifluoromethyl)phenyl]aniline;3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine;3'-(trifluoromethyl)-1,1'-biphenyl-4-amine;3'-(trifluoromethyl)[1,1'-biphenyl]-4-amine;MFCD03424686;SCHEMBL3793159;DTXSID201260069;3'-(Trifluoromethyl)biphenyl-4-amine;3'-Trifluoromethyl-biphenyl-4-ylamine;AKOS000124343;SB76915;LS-44160;NS-03222;BB 0222480;FT-0722023;EN300-30505;A873582;3-(TRIFLUOROMETHYL)[1,1-BIPHENYL]-4-AMINE;Z299629720

Suppliers and Price of 4-[3-(Trifluoromethyl)phenyl]aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-[3-(Trifluoromethyl)phenyl]aniline
1 g
$ 225.00

SynQuest Laboratories
4-[3-(Trifluoromethyl)phenyl]aniline
250 mg
$ 105.00

Crysdot
3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine 95+%
10g
$ 546.00

Crysdot
3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine 95+%
5g
$ 339.00

American Custom Chemicals Corporation
3'-TRIFLUOROMETHYL-BIPHENYL-4-YLAMINE 95.00%
5G
$ 1632.67

American Custom Chemicals Corporation
3'-TRIFLUOROMETHYL-BIPHENYL-4-YLAMINE 95.00%
2.5G
$ 1283.26

American Custom Chemicals Corporation
3'-TRIFLUOROMETHYL-BIPHENYL-4-YLAMINE 95.00%
1G
$ 881.65

Alichem
3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine
10g
$ 556.51

Alichem
3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine
5g
$ 345.42

AK Scientific
4-[3-(Trifluoromethyl)phenyl]aniline
5g
$ 531.00

Total 16 raw suppliers

Chemical Property of 4-[3-(Trifluoromethyl)phenyl]aniline

Chemical Property:

Boiling Point:317.4oC at 760 mmHg
Flash Point:141.5oC
PSA：26.02000
Density:1.245g/cm3
LogP:4.53580
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:237.07653381
Heavy Atom Count:17
Complexity:244

Purity/Quality:

97% ^*data from raw suppliers

4-[3-(Trifluoromethyl)phenyl]aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C(F)(F)F)C2=CC=C(C=C2)N

Technology Process of 4-[3-(Trifluoromethyl)phenyl]aniline

There total 10 articles about 4-[3-(Trifluoromethyl)phenyl]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 346-99-6
4-nitro-3'-(trifluoromethyl)-1,1'-biphenyl

: 397-28-4
4-amino-3'-(trifluoromethyl)-1,1'-biphenyl

Guidance literature:: With tin(ll) chloride; In ethanol; ethyl acetate; Heating;
DOI:10.1016/S1383-5718(01)00345-X

Reference yield: 94.0%

: 80460-73-7
(4-aminophenyl)boronic acid hydrochloride

: 401-78-5
3-bromo-1-trifluoromethylbenzene

: 397-28-4
4-amino-3'-(trifluoromethyl)-1,1'-biphenyl

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; at 75 ℃; for 12h; Reflux; Inert atmosphere;

Reference yield: 92.0%

: 401-81-0
m-trifluoromethylphenyl iodide

: 106-40-1
4-bromo-aniline

: 397-28-4
4-amino-3'-(trifluoromethyl)-1,1'-biphenyl

Guidance literature:: m-trifluoromethylphenyl iodide; With TurboGrignard; In tetrahydrofuran; at -20 ℃; for 1h; Inert atmosphere;

With lithium chlorozincate; In tetrahydrofuran; Inert atmosphere;

4-bromo-aniline; With bis(dibenzylideneacetone)-palladium⁽⁰⁾; ruphos; In tetrahydrofuran; at 25 ℃; for 0.0833333h; Inert atmosphere;
DOI:10.1021/ol1007026