Technology Process of (-)-(3S)-3-((benzyloxycarbonyl)amino)-4,4-dimethylpentanol
There total 5 articles about (-)-(3S)-3-((benzyloxycarbonyl)amino)-4,4-dimethylpentanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
n-butyllithium; ammonia borane; diisopropylamine;
In
tetrahydrofuran; hexane;
at 0 ℃;
for 2h;
DOI:10.1021/jo051207j
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 99 percent / Et3N / tetrahydrofuran / 1.5 h / -20 °C
2: 60 percent / TMEDA / tetrahydrofuran / -105 °C
3: H2 / Pd/C / ethanol / 18 h / 3361.46 Torr
4: 0.25 g / NaOH / dioxane; H2O / 18 h / 20 °C
5: 72 percent / n-BuLi; diisopropylamine; NH3*BH3 / tetrahydrofuran; hexane / 2 h / 0 °C
With
sodium hydroxide; n-butyllithium; ammonia borane; N,N,N,N,-tetramethylethylenediamine; hydrogen; triethylamine; diisopropylamine;
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; ethanol; hexane; water;
DOI:10.1021/jo051207j
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 60 percent / TMEDA / tetrahydrofuran / -105 °C
2: H2 / Pd/C / ethanol / 18 h / 3361.46 Torr
3: 0.25 g / NaOH / dioxane; H2O / 18 h / 20 °C
4: 72 percent / n-BuLi; diisopropylamine; NH3*BH3 / tetrahydrofuran; hexane / 2 h / 0 °C
With
sodium hydroxide; n-butyllithium; ammonia borane; N,N,N,N,-tetramethylethylenediamine; hydrogen; diisopropylamine;
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; ethanol; hexane; water;
DOI:10.1021/jo051207j
