5,5'-{4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene}dipent-4-ynyl dibenzoate

Base Information

Chemical Name:5,5'-{4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene}dipent-4-ynyl dibenzoate
CAS No.:1378950-93-6
Molecular Formula:C₅₄H₇₀O₆Si₂
Molecular Weight:871.317
Hs Code.:

Synonyms:5,5'-{4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene}dipent-4-ynyl dibenzoate

Suppliers and Price of 5,5'-{4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene}dipent-4-ynyl dibenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5,5'-{4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene}dipent-4-ynyl dibenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5,5'-{4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene}dipent-4-ynyl dibenzoate

There total 5 articles about 5,5'-{4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene}dipent-4-ynyl dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1378950-68-5
4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene bis-(trifluoromethanesulfonate)

: 100330-28-7
pent-4-yn-1-yl benzoate

: 1378950-93-6
5,5'-{4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene}dipent-4-ynyl dibenzoate

Guidance literature:: 4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene bis-(trifluoromethanesulfonate); With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; potassium iodide; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

pent-4-yn-1-yl benzoate; In N,N-dimethyl-formamide; at 70 ℃; regioselective reaction; Inert atmosphere;
DOI:10.1002/ejoc.201200079

Reference yield:

: 91-16-7
1,2-dimethoxybenzene

: 1378950-93-6
5,5'-{4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene}dipent-4-ynyl dibenzoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: iodine; periodic acid / methanol / 5 h / 70 °C / Inert atmosphere

2.1: boron tribromide / dichloromethane / 4 h / 0 °C / Inert atmosphere

3.1: pyridine / dichloromethane / 5 h / 0 °C / Inert atmosphere

3.2: 6.1 h / 20 °C / Inert atmosphere

4.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

5.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine; potassium iodide / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

5.2: 70 °C / Inert atmosphere

With pyridine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; iodine; boron tribromide; periodic acid; triethylamine; potassium iodide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; 4.1: Sonogashira coupling / 5.1: Sonogashira coupling / 5.2: Sonogashira coupling;
DOI:10.1002/ejoc.201200079

Reference yield:

: 1378950-54-9
4,5-diiodo-1,2-phenylene bis(trifluoromethanesulfonate)

: 1378950-93-6
5,5'-{4,5-bis[6-(tert-butyldimethylsilyloxy)hex-1-ynyl]-1,2-phenylene}dipent-4-ynyl dibenzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

2.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine; potassium iodide / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2.2: 70 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; potassium iodide; In tetrahydrofuran; N,N-dimethyl-formamide; 1.1: Sonogashira coupling / 2.1: Sonogashira coupling / 2.2: Sonogashira coupling;
DOI:10.1002/ejoc.201200079