Methanesulfonic acid (S)-1-[2-(diphenyl-phosphinoyl)-ethyl]-heptadecyl ester

Base Information

• Chemical Name: Methanesulfonic acid (S)-1-[2-(diphenyl-phosphinoyl)-ethyl]-heptadecyl ester
• CAS No.: 1027163-63-8
• Molecular Formula: C₃₂H₅₁O₄PS
• Molecular Weight: 562.794
• Mol file: 1027163-63-8.mol

Synonyms:Methanesulfonic acid (S)-1-[2-(diphenyl-phosphinoyl)-ethyl]-heptadecyl ester

Chemical Property of Methanesulfonic acid (S)-1-[2-(diphenyl-phosphinoyl)-ethyl]-heptadecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanesulfonic acid (S)-1-[2-(diphenyl-phosphinoyl)-ethyl]-heptadecyl ester

There total 6 articles about Methanesulfonic acid (S)-1-[2-(diphenyl-phosphinoyl)-ethyl]-heptadecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanesulfonyl chloride (124-63-0) + (S)-1-(Diphenyl-phosphinoyl)-nonadecan-3-ol → Methanesulfonic acid (S)-1-[2-(diphenyl-phosphinoyl)-ethyl]-heptadecyl ester (1027163-63-8)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃;

DOI:10.1016/S0040-4039(97)01234-3

Reference yield:

triphenylphosphine (603-35-0) → Methanesulfonic acid (S)-1-[2-(diphenyl-phosphinoyl)-ethyl]-heptadecyl ester (1027163-63-8)

Guidance literature:

Multi-step reaction with 3 steps

1: CaCO₃ / acetonitrile / 80 °C

2: 744 mg / NaOH / tetrahydrofuran; H₂O / 2 h / 50 °C

3: 100 percent / triethylamine / CH₂Cl₂ / 0.25 h / 0 °C

With sodium hydroxide; triethylamine; calcium carbonate; In tetrahydrofuran; dichloromethane; water; acetonitrile;

DOI:10.1016/S0040-4020(97)10099-0

Reference yield:

(S)-Nonadecane-1,3-diol → Methanesulfonic acid (S)-1-[2-(diphenyl-phosphinoyl)-ethyl]-heptadecyl ester (1027163-63-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 72 percent / hexamethylphosphoric triamide, iodine, triphenylphosphine / toluene / 1.5 h / Ambient temperature

2: CaCO₃ / acetonitrile / 80 °C

3: 744 mg / NaOH / tetrahydrofuran; H₂O / 2 h / 50 °C

4: 100 percent / triethylamine / CH₂Cl₂ / 0.25 h / 0 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; iodine; triethylamine; triphenylphosphine; calcium carbonate; In tetrahydrofuran; dichloromethane; water; toluene; acetonitrile;

DOI:10.1016/S0040-4020(97)10099-0

upstream raw materials:

methanesulfonyl chloride

triphenylphosphine

(S)-1-Iodo-nonadecan-3-ol

Downstream raw materials:

C₃₁H₄₇OP