C₄₇H₇₅NO₁₃

Base Information

• Chemical Name: C₄₇H₇₅NO₁₃
• CAS No.: 134628-60-7
• Molecular Formula: C₄₇H₇₅NO₁₃
• Molecular Weight: 862.111
• Mol file: 134628-60-7.mol

Synonyms:C₄₇H₇₅NO₁₃

Chemical Property of C₄₇H₇₅NO₁₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₇H₇₅NO₁₃

There total 21 articles about C₄₇H₇₅NO₁₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

benzyl bromide (100-39-0) + C40H69NO13 → C47H75NO13 (134628-60-7)

Guidance literature:

With 18-crown-6 ether; tetra-(n-butyl)ammonium iodide; potassium hydride; In tetrahydrofuran;

DOI:10.1021/ja00014a063

Reference yield:

C36H65NO12 (37398-66-6) → C47H75NO13 (134628-60-7)

Guidance literature:

Multi-step reaction with 15 steps

1: 95 percent / DMAP

2: NaBH₄ / methanol

3: H⁺

4: H₂ / 5percent Pd-C / ethanol

5: LiAlH₄

6: 1.) DMAP, 2.) NaH

7: DMAP

8: NaH, Bu₄NI

9: Et₃N

10: KH, 18-crown-6

11: Bu₄NF / tetrahydrofuran / Ambient temperature

12: pyridinium dichromate (PDC) / CH₂Cl₂

13: NaClO₂, 2-methyl-2-butene / 2-methyl-propan-2-ol; H₂O

14: Bu₄NF / hexamethylphosphoric acid triamide / 80 °C

15: 1.) 2,4,6-Cl₃C₆H₂COCl, Et₃N, 2.) DMAP / 1.) THF, 2.) toluene, reflux

With dmap; sodium chlorite; sodium tetrahydroborate; lithium aluminium tetrahydride; dipyridinium dichromate; 2-methyl-but-2-ene; 18-crown-6 ether; 2,4,6-trichlorobenzoyl chloride; tetrabutyl ammonium fluoride; hydrogen; hydrogen cation; tetra-(n-butyl)ammonium iodide; potassium hydride; sodium hydride; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; dichloromethane; water; tert-butyl alcohol;

DOI:10.1021/ja00014a063

Reference yield:

erythromycin B (527-75-3,40627-91-6,57172-63-1,66101-02-8) → C47H75NO13 (134628-60-7)

Guidance literature:

Multi-step reaction with 16 steps

1: 96 percent / I₂ / methanol / Irradiation

2: 95 percent / DMAP

3: NaBH₄ / methanol

4: H⁺

5: H₂ / 5percent Pd-C / ethanol

6: LiAlH₄

7: 1.) DMAP, 2.) NaH

8: DMAP

9: NaH, Bu₄NI

10: Et₃N

11: KH, 18-crown-6

12: Bu₄NF / tetrahydrofuran / Ambient temperature

13: pyridinium dichromate (PDC) / CH₂Cl₂

14: NaClO₂, 2-methyl-2-butene / 2-methyl-propan-2-ol; H₂O

15: Bu₄NF / hexamethylphosphoric acid triamide / 80 °C

16: 1.) 2,4,6-Cl₃C₆H₂COCl, Et₃N, 2.) DMAP / 1.) THF, 2.) toluene, reflux

With dmap; sodium chlorite; sodium tetrahydroborate; lithium aluminium tetrahydride; dipyridinium dichromate; 2-methyl-but-2-ene; 18-crown-6 ether; 2,4,6-trichlorobenzoyl chloride; tetrabutyl ammonium fluoride; hydrogen; iodine; hydrogen cation; tetra-(n-butyl)ammonium iodide; potassium hydride; sodium hydride; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; dichloromethane; water; tert-butyl alcohol;

DOI:10.1021/ja00014a063

upstream raw materials:

benzyl bromide

C₄₇H₇₇NO₁₄

C₃₆H₆₅NO₁₂

erythromycin B