2-(3-{[(5-amino-1,3-benzothiazol-2-yl)methyl]amino}-1,2,4-triazin-5-yl)-3-methylphenol

Base Information

Chemical Name:2-(3-{[(5-amino-1,3-benzothiazol-2-yl)methyl]amino}-1,2,4-triazin-5-yl)-3-methylphenol
CAS No.:1203604-18-5
Molecular Formula:C₁₈H₁₆N₆OS
Molecular Weight:364.431
Hs Code.:

Synonyms:2-(3-{[(5-amino-1,3-benzothiazol-2-yl)methyl]amino}-1,2,4-triazin-5-yl)-3-methylphenol

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Chemical Property of 2-(3-{[(5-amino-1,3-benzothiazol-2-yl)methyl]amino}-1,2,4-triazin-5-yl)-3-methylphenol

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Technology Process of 2-(3-{[(5-amino-1,3-benzothiazol-2-yl)methyl]amino}-1,2,4-triazin-5-yl)-3-methylphenol

There total 1 articles about 2-(3-{[(5-amino-1,3-benzothiazol-2-yl)methyl]amino}-1,2,4-triazin-5-yl)-3-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 1203605-20-2
2-(aminomethyl)-1,3-benzothiazol-5-amine

: 1203605-17-7
2-(3-chloro-1,2,4-triazin-5-yl)-3-methylphenol

: 1203604-18-5
2-(3-{[(5-amino-1,3-benzothiazol-2-yl)methyl]amino}-1,2,4-triazin-5-yl)-3-methylphenol

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 85 ℃; Inert atmosphere;

Reference yield: 7.0%

: 10200-59-6
Thiazole-2-carbaldehyde

: 1203604-18-5
2-(3-{[(5-amino-1,3-benzothiazol-2-yl)methyl]amino}-1,2,4-triazin-5-yl)-3-methylphenol

: 1203604-19-6
3-methyl-2-{3-[({5-[(1,3-thiazol-2-ylmethyl)amino]-1,3-benzothiazol-2-yl}methyl)amino]-1,2,4-triazin-5-yl}phenol

Guidance literature:: Thiazole-2-carbaldehyde; 2-(3-{[(5-amino-1,3-benzothiazol-2-yl)methyl]amino}-1,2,4-triazin-5-yl)-3-methylphenol; With titanium(IV) isopropylate; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Molecular sieve;

With sodium tetrahydroborate; In tetrahydrofuran; at 20 ℃; for 4h;