2,2,3,3,3-PENTAFLUOROPROPYLAMINE HYDROCHLORIDE

Base Information

• Chemical Name: 2,2,3,3,3-PENTAFLUOROPROPYLAMINE HYDROCHLORIDE
• CAS No.: 374-14-1
• Molecular Formula: C3H5ClF5N
• Molecular Weight: 185.524
• Hs Code.: 2923900090
• Mol file: 374-14-1.mol

Synonyms:1-Propanamine,2,2,3,3,3-pentafluoro-, hydrochloride (9CI);Propylamine,2,2,3,3,3-pentafluoro-, hydrochloride (7CI,8CI);2,2,3,3,3-Pentafluoropropylamine hydrochloride;

Chemical Property of 2,2,3,3,3-PENTAFLUOROPROPYLAMINE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 383mmHg at 25°C
• Melting Point: 248℃
• Boiling Point: 43 °C at 760 mmHg
• Flash Point: 15.1 °C
• PSA: 26.02000
• LogP: 2.64500

Purity/Quality:

98% ^*data from raw suppliers

2,2,3,3,3-PentafluoropropylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,2,3,3,3-Pentafluoropropylamine is used to prepare fluorinated diphenylpyridylethanamine-based cholesteryl ester transfer protein inhibitors.

Technology Process of 2,2,3,3,3-PENTAFLUOROPROPYLAMINE HYDROCHLORIDE

There total 2 articles about 2,2,3,3,3-PENTAFLUOROPROPYLAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pentafluoropropionic acid (422-64-0) + benzylamine (100-46-9) → 2,2,3,3,3-pentafluoropropylamine hydrochloride (374-14-1)

Guidance literature:

pentafluoropropionic acid; benzylamine; With tetrachloromethane; TEA; triphenylphosphine; In chloroform; at 80 ℃; for 0.666667h;

With TEA; water; at 80 ℃; for 12h;

With hydrogenchloride; In methanol; for 12h; Heating;

DOI:10.1016/S0040-4039(02)01104-8

Reference yield:

N-(2,2,3,3,3-pentafluoropropyl)benzamide (785-33-1) → 2,2,3,3,3-pentafluoropropylamine hydrochloride (374-14-1)

Guidance literature:

With hydrogenchloride; In methanol; for 24h; Heating;

DOI:10.1016/S0040-4039(02)01104-8

Reference yield: 99.0%

ethyl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate (14794-06-0) + 2,2,3,3,3-pentafluoropropylamine hydrochloride (374-14-1) → ethyl 4-[(3RS,6RS)-4,6-dioxo-3-(pentafluoroethyl)-3a,4,6,6a-tetrahydropyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoate

Guidance literature:

2,2,3,3,3-pentafluoropropylamine hydrochloride; With sodium nitrite; In dichloromethane; water; at 0 ℃; for 0.166667h;

ethyl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate; In dichloromethane; water; at 20 ℃; for 73h;

DOI:10.1002/chem.201304840

upstream raw materials:

N-(2,2,3,3,3-pentafluoropropyl)benzamide

pentafluoropropionic acid

benzylamine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 374-14-1 2,2,3,3,3-PENTAFLUOROPROPYLAMINE HYDROCHLORIDE

Send

Send

Metric Ton KG G Pound L ML

Send

Send