cis-2-phenyl-1,4-hexadiene

Base Information

• Chemical Name: cis-2-phenyl-1,4-hexadiene
• CAS No.: 60754-94-1
• Molecular Formula: C₁₂H₁₄
• Molecular Weight: 158.243
• Mol file: 60754-94-1.mol

Synonyms:cis-2-phenyl-1,4-hexadiene

Chemical Property of cis-2-phenyl-1,4-hexadiene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-2-phenyl-1,4-hexadiene

There total 5 articles about cis-2-phenyl-1,4-hexadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E/Z)-crotyl bromide (4784-77-4,29576-14-5,39616-19-8) + 1-bromovinylbenzene (98-81-7) → 3-methyl-2-phenyl-1,4-pentadiene (35342-71-3) + cis-2-phenyl-1,4-hexadiene (60754-94-1) + trans-2-phenyl-1,4-hexadiene (60754-95-2)

Guidance literature:

With indium; lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 100 ℃; for 1h;

DOI:10.1021/jo026121u

Reference yield:

2-methyl-2-phenyl[1,3]dithiolane (5769-02-8) + (E)-1-Bromo-2-butene (4784-77-4,39616-19-8,29576-14-5) → cis-2-phenyl-1,4-hexadiene (60754-94-1)

Guidance literature:

With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; magnesium; Yield given. Multistep reaction; 1.) Et₂O, 2.) Et₂O, benzene, reflux;

DOI:10.1021/jo00012a043

Reference yield:

phenylethynylmagnesium bromide (6738-06-3) + C4H7BrZn → cis-2-phenyl-1,4-hexadiene (60754-94-1)

Guidance literature:

Multistep reaction; (i) THF, (ii) aq. HCl;

upstream raw materials:

phenylethynylmagnesium bromide

phenylacetylene

lithium phenylacetylide

2-methyl-2-phenyl[1,3]dithiolane