7-(3-aminopropyl)-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane

Base Information

• Chemical Name: 7-(3-aminopropyl)-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane
• CAS No.: 117539-10-3
• Molecular Formula: C₅₄H₇₅N₇O₁₂S₅
• Molecular Weight: 1174.56
• Mol file: 117539-10-3.mol

Synonyms:7-(3-aminopropyl)-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane

Chemical Property of 7-(3-aminopropyl)-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-(3-aminopropyl)-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane

There total 2 articles about 7-(3-aminopropyl)-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

3-[4,10,16,19,22-Pentakis-(toluene-4-sulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaaza-cyclotetracos-7-yl]-propionitrile (117539-09-0) → 7-(3-aminopropyl)-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane (117539-10-3)

Guidance literature:

With diborane; In tetrahydrofuran;

DOI:10.1039/c39880000596

Reference yield:

4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane (107098-17-9) → 7-(3-aminopropyl)-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane (117539-10-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / tetrahydrofuran

2: 61 percent / B₂H₆ / tetrahydrofuran

With diborane; In tetrahydrofuran;

DOI:10.1039/c39880000596

Reference yield: 44.0%

9-Chloroacridine (1207-69-8) + 7-(3-aminopropyl)-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane (117539-10-3) → 7-<3-(9-acridinylamino)propyl>-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane (117539-11-4)

Guidance literature:

With phenol; at 80 ℃; for 6h;

DOI:10.1021/ja00166a025

upstream raw materials:

3-[4,10,16,19,22-Pentakis-(toluene-4-sulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaaza-cyclotetracos-7-yl]-propionitrile

4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane

Downstream raw materials:

7-<3-(9-acridinylamino)propyl>-4,10,16,19,22-pentakis(p-tolylsulfonyl)-1,13-dioxa-4,7,10,16,19,22-hexaazacyclotetracosane