4-(TRIFLUOROMETHYLTHIO)BENZENE-1,2-DIAMINE

Base Information

• Chemical Name: 4-(TRIFLUOROMETHYLTHIO)BENZENE-1,2-DIAMINE
• CAS No.: 370-46-7
• Molecular Formula: C7H7F3N2S
• Molecular Weight: 208.2
• Hs Code.: 2930909090
• Mol file: 370-46-7.mol

Synonyms:1,2-benzenediamine, 4-[(trifluoromethyl)thio]-;4-[(Trifluoromethyl)sulfanyl]benzene-1,2-diamine;4-(Trifluoromethylthio)phenylene-1,2-diamine;

Chemical Property of 4-(TRIFLUOROMETHYLTHIO)BENZENE-1,2-DIAMINE

Chemical Property:

• Refractive Index: 1.569
• Boiling Point: 236.683 °C at 760 mmHg
• Flash Point: 96.943 °C
• PSA: 77.34000
• Density: 1.452 g/cm³
• LogP: 3.62530
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-((Trifluoromethyl)thio)benzene-1,2-diamine 95+% ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

Useful:

Technology Process of 4-(TRIFLUOROMETHYLTHIO)BENZENE-1,2-DIAMINE

There total 3 articles about 4-(TRIFLUOROMETHYLTHIO)BENZENE-1,2-DIAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitro-4-trifluoromethylsulfanyl-aniline (404-74-0) → 4-trifluoromethylsulfanyl-o-phenylenediamine (370-46-7)

Guidance literature:

With hydrogenchloride; tin(ll) chloride;

DOI:10.1080/00304940309355835

Reference yield:

4-trifluoromethylthioacetanilide (351-81-5) → 4-trifluoromethylsulfanyl-o-phenylenediamine (370-46-7)

Guidance literature:

Multi-step reaction with 3 steps

1: HNO₃

2: aq.-ethanolic KOH

3: SnCl₂; aqueous HCl

With hydrogenchloride; potassium hydroxide; nitric acid; tin(ll) chloride;

DOI:10.1080/00304940309355835

Reference yield:

N-{2-nitro-4-[(trifluoromethyl)sulfanyl]phenyl}acetamide (448-41-9) → 4-trifluoromethylsulfanyl-o-phenylenediamine (370-46-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic KOH

2: SnCl₂; aqueous HCl

With hydrogenchloride; potassium hydroxide; tin(ll) chloride;

DOI:10.1080/00304940309355835

upstream raw materials:

2-nitro-4-trifluoromethylsulfanyl-aniline

4-trifluoromethylthioacetanilide

N-{2-nitro-4-[(trifluoromethyl)sulfanyl]phenyl}acetamide

Downstream raw materials:

N,N'-(4-trifluoromethylsulfanyl-o-phenylene)-bis-acetamide

2,3-diphenyl-6-trifluoromethylsulfanyl-quinoxaline