6-(4-Methoxyphenyl)nicotinic acid

Base Information

Chemical Name:6-(4-Methoxyphenyl)nicotinic acid
CAS No.:223127-23-9
Molecular Formula:C13H11 N O3
Molecular Weight:229.235
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70595251
Nikkaji Number:J2.066.851B
Wikidata:Q82490233
Mol file:223127-23-9.mol

Synonyms:6-(4-Methoxyphenyl)nicotinic acid;223127-23-9;6-(4-METHOXYPHENYL)PYRIDINE-3-CARBOXYLIC ACID;MFCD06410402;6-(4-Methoxy-phenyl)-nicotinic acid;6-(4-METHOXYPHENYL)-3-PYRIDINECARBOXYLIC ACID;SCHEMBL4228868;6-(4-Methoxyphenyl)nicotinicacid;DTXSID70595251;HTFUPRQBIIZYTE-UHFFFAOYSA-N;YIA12723;6-(4-Methoxyphenyl)-nicotinic acid;AC7644;AKOS016013770;AB24369;SY015205;TS-03266;DB-024472;CS-0302770;EN300-1628080;A878611

Suppliers and Price of 6-(4-Methoxyphenyl)nicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
6-(4-Methoxyphenyl)nicotinic acid
5 g
$ 1680.00

Matrix Scientific
6-(4-Methoxyphenyl)nicotinic acid 97%
1g
$ 488.00

Crysdot
6-(4-Methoxyphenyl)nicotinicacid 95+%
5g
$ 706.00

Chemenu
6-(4-Methoxyphenyl)nicotinicacid 95%
5g
$ 667.00

Atlantic Research Chemicals
6-(4-Methoxyphenyl)nicotinicacid 95%
1gm:
$ 187.33

American Custom Chemicals Corporation
6-(4-METHOXYPHENYL)PYRIDINE-3-CARBOXYLIC ACID 95.00%
10G
$ 3668.57

American Custom Chemicals Corporation
6-(4-METHOXYPHENYL)PYRIDINE-3-CARBOXYLIC ACID 95.00%
5G
$ 2152.64

American Custom Chemicals Corporation
6-(4-METHOXYPHENYL)PYRIDINE-3-CARBOXYLIC ACID 95.00%
1G
$ 1819.13

Alichem
6-(4-Methoxyphenyl)nicotinicacid
5g
$ 748.65

AK Scientific
6-(4-Methoxyphenyl)nicotinicacid
5g
$ 1072.00

Total 9 raw suppliers

Chemical Property of 6-(4-Methoxyphenyl)nicotinic acid

Chemical Property:

PSA：59.42000
LogP:2.45540
Storage Temp.:2-8°C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:229.07389321
Heavy Atom Count:17
Complexity:261

Purity/Quality:

97% ^*data from raw suppliers

6-(4-Methoxyphenyl)nicotinic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC=C(C=C2)C(=O)O

Technology Process of 6-(4-Methoxyphenyl)nicotinic acid

There total 3 articles about 6-(4-Methoxyphenyl)nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 223127-23-9
6-(4-methoxyphenyl)nicotinic acid

Guidance literature:: With lithium hydroxide monohydrate; In tetrahydrofuran; methanol; water;

Reference yield: 50.0%

: methyl 6-(4-methoxyphenyl) nicotinate

: 223127-23-9
6-(4-methoxyphenyl)nicotinic acid

Guidance literature:: methyl 6-(4-methoxyphenyl) nicotinate; With sodium hydroxide; In water; at 50 ℃;

With hydrogenchloride; In water;

Reference yield:

: 5326-23-8
6-Chloro-3-pyridinecarboxylic acid

: 5720-07-0
4-methoxyphenylboronic acid

: 223127-23-9
6-(4-methoxyphenyl)nicotinic acid

Guidance literature:: 6-Chloro-3-pyridinecarboxylic acid; With tritylchloride-polystyrene resin; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 18h;

4-methoxyphenylboronic acid; With potassium phosphate; phenyl-phospha-adamantane; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; water; at 20 ℃; for 15h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1.5h; Further stages.;
DOI:10.1016/j.tetlet.2004.05.110