2-(Difluoromethoxy)-4-fluoroaniline

Base Information

Chemical Name:2-(Difluoromethoxy)-4-fluoroaniline
CAS No.:832740-98-4
Molecular Formula:C₇H₆F₃NO
Molecular Weight:177.126
Hs Code.:2921490090
European Community (EC) Number:815-886-1
Mol file:832740-98-4.mol

Synonyms:2-(difluoromethoxy)-4-fluoroaniline;832740-98-4;2-Difluoromethoxy-4-fluoro-phenylamine;MFCD04969924;SCHEMBL2313110;2-Difluoromethoxy-4-fluoroaniline;YNDSRZNRALJMIX-UHFFFAOYSA-N;AMY37436;BBL039969;STK349646;AKOS000142639;CS-W000042;SB85554;AS-43799;EN300-91888;A922889

Suppliers and Price of 2-(Difluoromethoxy)-4-fluoroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-(Difluoromethoxy)-4-fluoroaniline
5 g
$ 672.00

SynQuest Laboratories
2-(Difluoromethoxy)-4-fluoroaniline
1 g
$ 264.00

Crysdot
2-Difluoromethoxy-4-fluoro-phenylamine 95+%
1g
$ 550.00

Apolloscientific
2-(Difluoromethoxy)-4-fluoroaniline
5g
$ 609.00

Apolloscientific
2-(Difluoromethoxy)-4-fluoroaniline
1g
$ 240.00

American Custom Chemicals Corporation
2-(DIFLUOROMETHOXY)-4-FLUOROANILINE 95.00%
5MG
$ 498.63

Alichem
2-Difluoromethoxy-4-fluoroaniline
250mg
$ 504.00

Alichem
2-Difluoromethoxy-4-fluoroaniline
1g
$ 1460.20

Alichem
2-Difluoromethoxy-4-fluoroaniline
500mg
$ 806.85

AK Scientific
2-(difluoromethoxy)-4-fluoroaniline
1g
$ 574.40

Total 5 raw suppliers

Chemical Property of 2-(Difluoromethoxy)-4-fluoroaniline

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:177.04014830
Heavy Atom Count:12
Complexity:145

Purity/Quality:

97% ^*data from raw suppliers

2-(Difluoromethoxy)-4-fluoroaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)OC(F)F)N

Technology Process of 2-(Difluoromethoxy)-4-fluoroaniline

There total 2 articles about 2-(Difluoromethoxy)-4-fluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.74%

: 1214329-62-0
2-(difluoromethoxy)-4-fluoro-1-nitro-benzene

: 832740-98-4
2-(difluoromethoxy)-4-fluoro-1-aniline

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃;

Reference yield:

: 446-36-6
5-fluoro-2-nitrophenol

: 832740-98-4
2-(difluoromethoxy)-4-fluoro-1-aniline

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 0.33 h / 20 °C

1.2: 3.5 h / 20 - 90 °C

2.1: hydrogen; palladium 10% on activated carbon / ethanol / 15 h / 20 °C

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In ethanol; N,N-dimethyl-formamide;