C₅₃H₆₈N₆O₁₀S

Base Information

• Chemical Name: C₅₃H₆₈N₆O₁₀S
• CAS No.: 183947-73-1
• Molecular Formula: C₅₃H₆₈N₆O₁₀S
• Molecular Weight: 981.223
• Mol file: 183947-73-1.mol

Synonyms:C₅₃H₆₈N₆O₁₀S

Chemical Property of C₅₃H₆₈N₆O₁₀S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₃H₆₈N₆O₁₀S

There total 10 articles about C₅₃H₆₈N₆O₁₀S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

C55H72N6O10S (162554-08-7) → C53H68N6O10S (183947-73-1)

Guidance literature:

With lithium hydroxide; In 1,4-dioxane; at 45 ℃;

DOI:10.1021/ja9607805

Reference yield:

4-{4-[((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-methyl]-benzyl}-benzoic acid methyl ester (183947-71-9) → C53H68N6O10S (183947-73-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 83 percent / H₂ / Pd/C

2: 74 percent / K₂CO₃ / CHCl₃ / Heating

3: 81 percent / pyridine / Heating

4: 76 percent / aq. LiOH / dioxane / 45 °C

With pyridine; lithium hydroxide; hydrogen; potassium carbonate; palladium on activated charcoal; In 1,4-dioxane; chloroform;

DOI:10.1021/ja9607805

Reference yield:

Boc-Lys(Z)-OH (2389-45-9) → C53H68N6O10S (183947-73-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 54 percent / HOBt, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide / tetrahydrofuran

2: 83 percent / H₂ / Pd/C

3: 74 percent / K₂CO₃ / CHCl₃ / Heating

4: 81 percent / pyridine / Heating

5: 76 percent / aq. LiOH / dioxane / 45 °C

With pyridine; lithium hydroxide; hydrogen; potassium carbonate; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; chloroform;

DOI:10.1021/ja9607805

upstream raw materials:

C₅₅H₇₂N₆O₁₀S

Boc-Lys(Z)-OH

4-{4-[((S)-6-Amino-2-tert-butoxycarbonylamino-hexanoylamino)-methyl]-benzyl}-benzoic acid methyl ester

4-{4-[((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-methyl]-benzyl}-benzoic acid methyl ester