2-[5-(3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-2-oxo-butyl)-tetrahydro-furan-2-yl]-propionaldehyde

Base Information

Chemical Name:2-[5-(3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-2-oxo-butyl)-tetrahydro-furan-2-yl]-propionaldehyde
CAS No.:919608-44-9
Molecular Formula:C₃₁H₄₆O₆
Molecular Weight:514.703
Hs Code.:

Synonyms:2-[5-(3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-2-oxo-butyl)-tetrahydro-furan-2-yl]-propionaldehyde

Suppliers and Price of 2-[5-(3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-2-oxo-butyl)-tetrahydro-furan-2-yl]-propionaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[5-(3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-2-oxo-butyl)-tetrahydro-furan-2-yl]-propionaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[5-(3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-2-oxo-butyl)-tetrahydro-furan-2-yl]-propionaldehyde

There total 26 articles about 2-[5-(3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-2-oxo-butyl)-tetrahydro-furan-2-yl]-propionaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 919608-49-4
3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-1-[5-(2-hydroxy-1-methyl-ethyl)-tetrahydro-furan-2-yl]-butan-2-ol

: 919608-44-9
2-[5-(3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-2-oxo-butyl)-tetrahydro-furan-2-yl]-propionaldehyde

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1002/anie.200602860

Reference yield:

: 919608-28-9
3-[5-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3-hydroxy-2-methyl-pentanoyl]-4-methyl-5-phenyl-oxazolidin-2-one

: 919608-44-9
2-[5-(3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-2-oxo-butyl)-tetrahydro-furan-2-yl]-propionaldehyde

Guidance literature:: Multi-step reaction with 9 steps

1.1: lithium borohydride / diethyl ether; tetrahydrofuran / 0 - 20 °C

2.1: 3.59 g / imidazole / CH₂Cl₂ / 1 h / 20 °C

3.1: 98 percent / TEA / CH₂Cl₂ / 0 - 20 °C

4.1: 84 percent / CSA; methanol / 2 h / 20 °C

5.1: 80 percent / sodium hexamethyldisilazide / tetrahydrofuran / 0 - 20 °C

6.1: 89 percent / SO₃*pyridine; TEA; DMSO / CH₂Cl₂ / 0.5 h / 20 °C

7.1: 557 mg / tetrahydrofuran; hexane / -78 - 20 °C

8.1: 85 percent / m-CPBA / CH₂Cl₂ / 3 h

9.1: lithium aluminum hydride / diethyl ether / 12 h

9.2: 30 mg / Dess-Martin periodinane / CH₂Cl₂ / 1 h / 20 °C

With 1H-imidazole; methanol; lithium aluminium tetrahydride; lithium borohydride; pyridine-SO₃ complex; TEA; camphor-10-sulfonic acid; sodium hexamethyldisilazane; dimethyl sulfoxide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; 5.1: Williamson ether synthesis / 7.1: Wittig olefination / 9.2: Dess-Martin oxidation;
DOI:10.1016/j.tet.2007.07.005

Reference yield:

: 919608-12-1
1-(tert-butyl-diphenyl-silanyloxy)-5-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-pentan-3-ol

: 919608-44-9
2-[5-(3-{5-[2-benzyloxy-3-(5-methyl-tetrahydro-furan-2-yl)-butyl]-tetrahydro-furan-2-yl}-2-oxo-butyl)-tetrahydro-furan-2-yl]-propionaldehyde

Guidance literature:: Multi-step reaction with 7 steps

1.1: 98 percent / TEA / CH₂Cl₂ / 0 - 20 °C

2.1: 84 percent / CSA; methanol / 2 h / 20 °C

3.1: 80 percent / sodium hexamethyldisilazide / tetrahydrofuran / 0 - 20 °C

4.1: 89 percent / SO₃*pyridine; TEA; DMSO / CH₂Cl₂ / 0.5 h / 20 °C

5.1: 557 mg / tetrahydrofuran; hexane / -78 - 20 °C

6.1: 85 percent / m-CPBA / CH₂Cl₂ / 3 h

7.1: lithium aluminum hydride / diethyl ether / 12 h

7.2: 30 mg / Dess-Martin periodinane / CH₂Cl₂ / 1 h / 20 °C

With methanol; lithium aluminium tetrahydride; pyridine-SO₃ complex; TEA; camphor-10-sulfonic acid; sodium hexamethyldisilazane; dimethyl sulfoxide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; 3.1: Williamson ether synthesis / 5.1: Wittig olefination / 7.2: Dess-Martin oxidation;
DOI:10.1016/j.tet.2007.07.005