cyclohexanecarboxylic acid{(1R)-2-[4-(2-methoxy-phenyl)-piperidin-1-yl]-1-pyridin-4-ylmethyl-ethyl}-methyl-amide

Base Information

Chemical Name:cyclohexanecarboxylic acid{(1R)-2-[4-(2-methoxy-phenyl)-piperidin-1-yl]-1-pyridin-4-ylmethyl-ethyl}-methyl-amide
CAS No.:277296-73-8
Molecular Formula:C₂₈H₃₉N₃O₂
Molecular Weight:449.637
Hs Code.:

Synonyms:cyclohexanecarboxylic acid{(1R)-2-[4-(2-methoxy-phenyl)-piperidin-1-yl]-1-pyridin-4-ylmethyl-ethyl}-methyl-amide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of cyclohexanecarboxylic acid{(1R)-2-[4-(2-methoxy-phenyl)-piperidin-1-yl]-1-pyridin-4-ylmethyl-ethyl}-methyl-amide

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Technology Process of cyclohexanecarboxylic acid{(1R)-2-[4-(2-methoxy-phenyl)-piperidin-1-yl]-1-pyridin-4-ylmethyl-ethyl}-methyl-amide

There total 2 articles about cyclohexanecarboxylic acid{(1R)-2-[4-(2-methoxy-phenyl)-piperidin-1-yl]-1-pyridin-4-ylmethyl-ethyl}-methyl-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 277296-92-1
C₂₁H₂₉N₃O

: 2719-27-9
cyclohexanylcarbonyl chloride

: 277296-73-8
cyclohexanecarboxylic acid{(1R)-2-[4-(2-methoxy-phenyl)-piperidin-1-yl]-1-pyridin-4-ylmethyl-ethyl}-methyl-amide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;

Reference yield:

BH_3.THF: BH_3.THF

: 37535-58-3
(R)-2-(tert-butoxycarbonylamino)-3-(pyridin-4-yl)propanoic acid

: 154422-95-4
1,2,3,6-tetrahydro-4-(2-methoxyphenyl)pyridine

: 2719-27-9
cyclohexanylcarbonyl chloride

: 277296-73-8
cyclohexanecarboxylic acid{(1R)-2-[4-(2-methoxy-phenyl)-piperidin-1-yl]-1-pyridin-4-ylmethyl-ethyl}-methyl-amide

Guidance literature:: With formic acid; N-methyl-2-indolinone; acetic anhydride; sodium hydrogencarbonate; benzotriazol-1-ol; triethylamine; In 1,4-dioxane; hydrogenchloride; dichloromethane; water; N,N-dimethyl-formamide;