phenylacetaldehyde dimethylhydrazone

Base Information

• Chemical Name: phenylacetaldehyde dimethylhydrazone
• CAS No.: 65259-56-5
• Molecular Formula: C₁₀H₁₄N₂
• Molecular Weight: 162.235
• Mol file: 65259-56-5.mol

Synonyms:phenylacetaldehyde dimethylhydrazone

Chemical Property of phenylacetaldehyde dimethylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenylacetaldehyde dimethylhydrazone

There total 4 articles about phenylacetaldehyde dimethylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

phenethyl azide (6926-44-9) + N,N-Dimethylhydrazine (57-14-7) → phenylacetaldehyde dimethylhydrazone (65259-56-5)

Guidance literature:

iron(III) chloride; In acetonitrile; for 17h; Heating;

DOI:10.1021/jo000708w

Reference yield: 88.0%

phenylacetaldehyde (122-78-1) + N,N-Dimethylhydrazine (57-14-7) → phenylacetaldehyde dimethylhydrazone (65259-56-5)

Guidance literature:

at 0 - 20 ℃; for 4h; Inert atmosphere;

DOI:10.1080/00397911.2021.2008449

Reference yield:

1-phenyl-2-bromoethane (103-63-9) → phenylacetaldehyde dimethylhydrazone (65259-56-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NaN₃ / acetonitrile / 16 h / 20 °C

2: FeCl₃*6H₂O / acetonitrile / 18 h / Heating

With sodium azide; iron(III) chloride; In acetonitrile; 1: Substitution / 2: Condensation;

upstream raw materials:

phenethyl azide

N,N-Dimethylhydrazine

1-phenyl-2-bromoethane

phenylacetylene

Downstream raw materials:

1,1-Dimethyl-2-(2-phenylvinyl)-2-(trimethylsilyl)hydrazin

(E)-benzeneacetaldehyde (E)-2-phenylpropionaldehydedimethylhydrazone

Ethoxyphenylacetaldehyd-dimethylhydrazon

(Ethylthio)phenylacetaldehyd-dimethylhydrazon