2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-6,7-dihydro-5H-cyclopentapyrimidine

Base Information

Chemical Name:2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-6,7-dihydro-5H-cyclopentapyrimidine
CAS No.:78042-89-4
Molecular Formula:C₂₄H₂₆N₄O
Molecular Weight:386.497
Hs Code.:

Synonyms:2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-6,7-dihydro-5H-cyclopentapyrimidine

Suppliers and Price of 2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-6,7-dihydro-5H-cyclopentapyrimidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-6,7-dihydro-5H-cyclopentapyrimidine

Chemical Property:

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Technology Process of 2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-6,7-dihydro-5H-cyclopentapyrimidine

There total 3 articles about 2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-6,7-dihydro-5H-cyclopentapyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 2759-28-6
1-phenylmethylpiperazine

: 81532-50-5
2-chloro-4-phenoxy-5,6-trimethylenepyrimidine

: 78042-89-4
2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-6,7-dihydro-5H-cyclopentapyrimidine

Guidance literature:: In i-Amyl alcohol; at 180 ℃; for 6.5h;

Reference yield:

: 5466-43-3
2,4-dichloro-6,7-dihydro-5H-cyclopentapyrimidine

: 78042-89-4
2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-6,7-dihydro-5H-cyclopentapyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / 1,8-diazabicyclo(5,4,0)-7-undecene / dimethylformamide / 3 h / 100 °C

2: 71 percent / 3-methyl-butan-1-ol / 6.5 h / 180 °C

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In i-Amyl alcohol; N,N-dimethyl-formamide;

Reference yield:

: 108-95-2,27073-41-2
phenol

: 78042-89-4
2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-6,7-dihydro-5H-cyclopentapyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / 1,8-diazabicyclo(5,4,0)-7-undecene / dimethylformamide / 3 h / 100 °C

2: 71 percent / 3-methyl-butan-1-ol / 6.5 h / 180 °C

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In i-Amyl alcohol; N,N-dimethyl-formamide;