N-(phenylmethoxy)-N-2-butenylcarbamic acid 1,1-dimethylethyl ester

Base Information

• Chemical Name: N-(phenylmethoxy)-N-2-butenylcarbamic acid 1,1-dimethylethyl ester
• CAS No.: 1401981-68-7
• Molecular Formula: C₁₆H₂₃NO₃
• Molecular Weight: 277.364
• Mol file: 1401981-68-7.mol

Synonyms:N-(phenylmethoxy)-N-2-butenylcarbamic acid 1,1-dimethylethyl ester

Chemical Property of N-(phenylmethoxy)-N-2-butenylcarbamic acid 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N-(phenylmethoxy)-N-2-butenylcarbamic acid 1,1-dimethylethyl ester

There total 2 articles about N-(phenylmethoxy)-N-2-butenylcarbamic acid 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(E/Z)-crotyl bromide (4784-77-4,29576-14-5,39616-19-8) + tert-butyl N-(benzyloxy)carbamate (79722-21-7) → N-(phenylmethoxy)-N-2-butenylcarbamic acid 1,1-dimethylethyl ester (1401981-68-7)

Guidance literature:

tert-butyl N-(benzyloxy)carbamate; With sodium hydride;

(E/Z)-crotyl bromide;

DOI:10.1021/jo402544p

Reference yield:

crotyl acetate (628-08-0) + tert-butyl N-(benzyloxy)carbamate (79722-21-7) → N-(phenylmethoxy)-N-2-butenylcarbamic acid 1,1-dimethylethyl ester (1401981-68-7) + C16H23NO3

Guidance literature:

With sodium hydride; 1,2-bis-(diphenylphosphino)ethane; In tetrahydrofuran; regioselective reaction;

DOI:10.1016/j.mcat.2020.111221

Reference yield:

N-(phenylmethoxy)-N-2-butenylcarbamic acid 1,1-dimethylethyl ester (1401981-68-7) → C11H15NO

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 5h; Inert atmosphere;

DOI:10.1021/jo3015227

upstream raw materials:

(E/Z)-crotyl bromide

tert-butyl N-(benzyloxy)carbamate

crotyl acetate

Downstream raw materials:

N-2-buten-1-yl-2-methyl-N-(phenylmethoxy)-2-propenamide

tert-butyl but-2-en-1-ylcarbamate