N,N',N''-tri-p-tosyl-2,11,20-triaza<3.3.3>(2,6)pyridinophane

Base Information

• Chemical Name: N,N',N''-tri-p-tosyl-2,11,20-triaza<3.3.3>(2,6)pyridinophane
• CAS No.: 115078-42-7
• Molecular Formula: C₄₂H₄₂N₆O₆S₃
• Molecular Weight: 823.03
• Mol file: 115078-42-7.mol

Synonyms:N,N',N''-tri-p-tosyl-2,11,20-triaza<3.3.3>(2,6)pyridinophane

Chemical Property of N,N',N''-tri-p-tosyl-2,11,20-triaza<3.3.3>(2,6)pyridinophane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N',N''-tri-p-tosyl-2,11,20-triaza<3.3.3>(2,6)pyridinophane

There total 24 articles about N,N',N''-tri-p-tosyl-2,11,20-triaza<3.3.3>(2,6)pyridinophane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2,6-bis<(p-tosylamino)methyl>pyridine (112633-27-9) + N,N-bis[[6-(bromomethyl)pyridine-2yl]methyl]-p-tosylamide (183382-76-5) → N,N',N''-tri-p-tosyl-2,11,20-triaza<3.3.3>(2,6)pyridinophane (115078-42-7)

Guidance literature:

With potassium hydroxide; tetra-(n-butyl)ammonium iodide; In dichloromethane; water; for 29h; Heating;

DOI:10.1021/jo961081d

Reference yield: 58.0%

sodium p-toluenesulfonamide (18522-92-4) + pyridine-2,6-diylbis(methylene)dimethanesulfonate (55667-74-8) → C28H28N4O4S2*ClH + N,N',N''-tri-p-tosyl-2,11,20-triaza<3.3.3>(2,6)pyridinophane (115078-42-7)

Guidance literature:

sodium p-toluenesulfonamide; pyridine-2,6-diylbis(methylene)dimethanesulfonate; In N,N-dimethyl-formamide; at 80 ℃; for 60h; Inert atmosphere;

With hydrogenchloride; In ethanol; water; Inert atmosphere;

DOI:10.1039/c7ob02508d

Reference yield: 39.0%

2,6-bis[(tosyloxy)methyl]pyridine (112633-26-8) + sodium p-toluenesulfonamide (18522-92-4) → C28H28N4O4S2*ClH + N,N',N''-tri-p-tosyl-2,11,20-triaza<3.3.3>(2,6)pyridinophane (115078-42-7)

Guidance literature:

2,6-bis[(tosyloxy)methyl]pyridine; sodium p-toluenesulfonamide; In N,N-dimethyl-formamide; at 80 ℃; for 60h; Inert atmosphere;

With hydrogenchloride; In ethanol; water; Inert atmosphere;

DOI:10.1039/c7ob02508d

upstream raw materials:

2,6-bis(chloromethyl)pyridine

sodium p-toluenesulfonamide

2,6-bis<(p-tosylamino)methyl>pyridine

N,N-bis[[6-(bromomethyl)pyridine-2yl]methyl]-p-tosylamide