3-Pyrrolidinemethanol,4-phenyl-1-(phenylmethyl)-, (3R,4S)-

Base Information Edit

Chemical Name:3-Pyrrolidinemethanol,4-phenyl-1-(phenylmethyl)-, (3R,4S)-
CAS No.:221141-87-3
Molecular Formula:C18H21 N O
Molecular Weight:267.371
Hs Code.:
Mol file:221141-87-3.mol

Synonyms:1-Benzyl-3-(R)-hydroxymethyl-4-(S)-phenylpyrrolidine

Suppliers and Price of 3-Pyrrolidinemethanol,4-phenyl-1-(phenylmethyl)-, (3R,4S)-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-BENZYL-4-PHENYL-3-PYRROLIDINEMETHANOL 95.00%
5MG
$ 502.74

Total 2 raw suppliers

Chemical Property of 3-Pyrrolidinemethanol,4-phenyl-1-(phenylmethyl)-, (3R,4S)- Edit

Chemical Property:

Vapor Pressure:8.99E-07mmHg at 25°C
Refractive Index:1.595
Boiling Point:389.7°Cat760mmHg
Flash Point:181.3°C
PSA：23.47000
Density:1.11g/cm³
LogP:2.83240

Purity/Quality:

99% ^*data from raw suppliers

1-BENZYL-4-PHENYL-3-PYRROLIDINEMETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-Pyrrolidinemethanol,4-phenyl-1-(phenylmethyl)-, (3R,4S)-

There total 7 articles about 3-Pyrrolidinemethanol,4-phenyl-1-(phenylmethyl)-, (3R,4S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.9%

: 1201574-92-6,80896-73-7,1821739-17-6
(3R,4S)-1-benzyl-4-phenylpyrrolidine-3-carboxylic acid

: 221141-87-3
[(3R,4S)-1-benzyl-4-phenylpyrrolidin-3-yl]methanol

Guidance literature:: (3R,4S)-1-benzyl-4-phenylpyrrolidine-3-carboxylic acid; With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; at 14 - 30 ℃; for 3h; Inert atmosphere;

With water; sodium hydroxide; In toluene;

Reference yield: 69.0%

: 221141-86-2
(S)-4-Benzyl-3-((3R,4S)-1-benzyl-4-phenyl-pyrrolidine-3-carbonyl)-oxazolidin-2-one

: 221141-87-3
[(3R,4S)-1-benzyl-4-phenylpyrrolidin-3-yl]methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1016/S0960-894X(01)00232-3

Reference yield: 55.0%

: 189498-44-0
(S)-3-((3R,4S)-1-benzyl-4-phenyl-pyrrolidine-3-carbonyl)-4-phenyl-oxazolidin-2-one

: 221141-87-3
[(3R,4S)-1-benzyl-4-phenylpyrrolidin-3-yl]methanol

Guidance literature:: (S)-3-((3R,4S)-1-benzyl-4-phenyl-pyrrolidine-3-carbonyl)-4-phenyl-oxazolidin-2-one; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 - 40 ℃;

With sodium hydroxide; water; In tetrahydrofuran; for 0.25h;