(4-Phenylpyrrolidin-3-yl)methanol

Base Information

Chemical Name:(4-Phenylpyrrolidin-3-yl)methanol
CAS No.:848307-24-4
Molecular Formula:C11H15NO
Molecular Weight:177.246
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40536595
Mol file:848307-24-4.mol

Synonyms:(4-phenylpyrrolidin-3-yl)methanol;55438-50-1;3-(SR)-hydroxymethyl-4-(SR)-phenylpyrrolidine;SCHEMBL1239831;DTXSID40536595;MMDOXIYRYUVGPQ-UHFFFAOYSA-N;AKOS004119320;F1908-1449

Suppliers and Price of (4-Phenylpyrrolidin-3-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
((3R,4S)-4-PHENYLPYRROLIDIN-3-YL)METHANOL 95.00%
1G
$ 990.15

American Custom Chemicals Corporation
((3R,4S)-4-PHENYLPYRROLIDIN-3-YL)METHANOL 95.00%
5MG
$ 505.98

Total 14 raw suppliers

Chemical Property of (4-Phenylpyrrolidin-3-yl)methanol

Chemical Property:

Vapor Pressure:0.000177mmHg at 25°C
Refractive Index:1.538
Boiling Point:316.1 °C at 760 mmHg
PKA:14.93±0.10(Predicted)
Flash Point:135.7 °C
PSA：32.26000
Density:1.058 g/cm³
LogP:1.31070
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:177.115364102
Heavy Atom Count:13
Complexity:154

Purity/Quality:

97% ^*data from raw suppliers

((3R,4S)-4-PHENYLPYRROLIDIN-3-YL)METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(CN1)C2=CC=CC=C2)CO

Technology Process of (4-Phenylpyrrolidin-3-yl)methanol

There total 4 articles about (4-Phenylpyrrolidin-3-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 848307-25-5
(3R,4S)-tert-butyl 3-(hydroxymethyl)-4-phenylpyrrolidine-1-carboxylate

: 848307-24-4
(3R,4S)-3-hydroxymethyl-4-phenylpyrrolidine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; toluene; for 0.5h;
DOI:10.1021/acs.orglett.6b00293

Reference yield: 79.0%

: methyl (3R,4S)-2-oxo-4-phenylpyrrolidine-3-carboxylate

: 848307-24-4
(3R,4S)-3-hydroxymethyl-4-phenylpyrrolidine

Guidance literature:: methyl (3R,4S)-2-oxo-4-phenylpyrrolidine-3-carboxylate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 60 ℃; for 12h; Reflux;

With water; In tetrahydrofuran; at 20 ℃; for 0.166667h;
DOI:10.1016/j.bmc.2014.06.056

Reference yield:

: 221141-87-3
[(3R,4S)-1-benzyl-4-phenylpyrrolidin-3-yl]methanol

: 848307-24-4
(3R,4S)-3-hydroxymethyl-4-phenylpyrrolidine

Guidance literature:: [(3R,4S)-1-benzyl-4-phenylpyrrolidin-3-yl]methanol; With ammonium formate; palladium dihydroxide; In ehanol; for 1.5h; Heating / reflux;

With ammonia; In methanol; ethanol; for 0.5h; Heating / reflux;