Ethyl 2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate

Base Information

Chemical Name:Ethyl 2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate
CAS No.:221136-66-9
Molecular Formula:C9H11 Br N2 O3
Molecular Weight:275.102
Hs Code.:
European Community (EC) Number:606-937-7
DSSTox Substance ID:DTXSID10363835
Wikidata:Q82147583
Mol file:221136-66-9.mol

Synonyms:221136-66-9;Ethyl 2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate;3-Bromo-6-methyl-2-oxo-1(2H)-pyrazineacetic acid ethyl ester;ethyl 2-(3-bromo-6-methyl-2-oxopyrazin-1-yl)acetate;3-bromo-6-methyl-1-(ethoxycarbonylmethyl)pyrazinone;3-Bromo-1-(ethoxycarbonylmethyl)-6-methylpyrazinone;SCHEMBL4901672;Ethyl (3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate;DTXSID10363835;1(2H)-Pyrazineaceticacid, 3-bromo-6-methyl-2-oxo-, ethyl ester;MFCD04038518;AKOS015917806;BS-16538;CS-0187396;FT-0686801;C74120;Ethyl (3-bromo-6-methyl-2-oxo-2H-pyrazin-1-yl)-acetate;Ethyl2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate;(3-bromo-6-methyl-2-oxo-2H-pyrazin-1-yl)-acetic acid ethyl ester

Suppliers and Price of Ethyl 2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
Ethyl2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate 95%+
100mg
$ 290.00

American Custom Chemicals Corporation
3-BROMO-6-METHYL-2-OXO-1(2H)-PYRAZINEACETIC ACID ETHYL ESTER 95.00%
5MG
$ 505.99

Ambeed
Ethyl2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate 95%
250mg
$ 442.00

Ambeed
Ethyl2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate 95%
100mg
$ 222.00

Total 12 raw suppliers

Chemical Property of Ethyl 2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate

Chemical Property:

Vapor Pressure:9.89E-05mmHg at 25°C
Refractive Index:1.58
Boiling Point:338.3°Cat760mmHg
Flash Point:158.4°C
PSA：61.19000
Density:1.55g/cm³
LogP:0.87730
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:273.99530
Heavy Atom Count:15
Complexity:349

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CN1C(=CN=C(C1=O)Br)C

Technology Process of Ethyl 2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate

There total 6 articles about Ethyl 2-(3-bromo-6-methyl-2-oxopyrazin-1(2H)-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: phosphorous oxybromide

: 221136-61-4
Ethyl (3-hydroxy-6-methyl-2-oxo-2H-pyrazin-1-yl)-acetate

: 221136-66-9
3-bromo-1-(ethoxycarbonylmethyl)-6-methylpyrazinone

Guidance literature:: In hexane; chloroform;

Reference yield: 87.0%

: 221136-61-4
3,4-dihydro-6-methyl-2,3-dioxo-1(2H)-pyrazineacetic acid ethyl ester

: 221136-66-9
3-bromo-1-(ethoxycarbonylmethyl)-6-methylpyrazinone

Guidance literature:: With disodium hydrogenphosphate; phosphorus(V) oxybromide; In 1,2-dichloro-ethane; at 50 ℃; for 18h;
DOI:10.1080/00397910008086927

Reference yield:

: 221136-49-8
[[2-[(2-hydroxypropyl)amino]-1,2-dioxoethyl]amino]acetic acid ethyl ester

: 221136-66-9
3-bromo-1-(ethoxycarbonylmethyl)-6-methylpyrazinone

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / RuCl₃; aq. NaBrO₃

2: TFAA / 80 °C

3: POBr₃; aq. NH₃ / Heating

With ruthenium trichloride; ammonium hydroxide; sodium bromate; trifluoroacetic anhydride; phosphorus(V) oxybromide;
DOI:10.1016/S0960-894X(02)00129-4