1-(Furo[2,3-b]pyridin-5-yl)ethanone

Base Information

• Chemical Name: 1-(Furo[2,3-b]pyridin-5-yl)ethanone
• CAS No.: 220957-41-5
• Molecular Formula: C₉H₇NO₂
• Molecular Weight: 161.16
• DSSTox Substance ID: DTXSID001299456
• Nikkaji Number: J1.047.975D
• Mol file: 220957-41-5.mol

Synonyms:1-(furo[2,3-b]pyridin-5-yl)ethanone;220957-41-5;1-furo[2,3-b]pyridin-5-ylethanone;5-Acetylfuro[2,3-b]pyridine;SCHEMBL1101166;DTXSID001299456;1-furo[2,3-b]pyridin-5-yl-Ethanone;AB91278

Chemical Property of 1-(Furo[2,3-b]pyridin-5-yl)ethanone

Chemical Property:

• Boiling Point: 256.5±20.0 °C(Predicted)
• PKA: 1.60±0.40(Predicted)
• PSA: 43.10000
• Density: 1.229±0.06 g/cm3(Predicted)
• LogP: 2.03040
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 161.047678466
• Heavy Atom Count: 12
• Complexity: 193

Purity/Quality:

99% ^*data from raw suppliers

1-(Furo[2,3-b]pyridin-5-yl)ethanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)C1=CN=C2C(=C1)C=CO2

Technology Process of 1-(Furo[2,3-b]pyridin-5-yl)ethanone

There total 2 articles about 1-(Furo[2,3-b]pyridin-5-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methylmagnesium bromide (75-16-1) + 5-cyanofuro<2,3-b>pyridine (220957-36-8) → 5-acetylfuro<2,3-b>pyridine (220957-41-5)

Guidance literature:

With sulfuric acid; Yield given; Multistep reaction; 1.) THF, RT, 2 h, 2.) 5 min;

DOI:10.1002/jhet.5570350611

Reference yield:

→ 5-acetylfuro<2,3-b>pyridine (220957-41-5)

Guidance literature:

upstream raw materials:

methylmagnesium bromide

5-cyanofuro<2,3-b>pyridine