4-[tert-Butylamino-(dimethoxy-phosphoryl)-methyl]-benzoic acid

Base Information

• Chemical Name: 4-[tert-Butylamino-(dimethoxy-phosphoryl)-methyl]-benzoic acid
• CAS No.: 176903-54-1
• Molecular Formula: C₁₄H₂₂NO₅P
• Molecular Weight: 315.306
• Mol file: 176903-54-1.mol

Synonyms:4-[tert-Butylamino-(dimethoxy-phosphoryl)-methyl]-benzoic acid

Chemical Property of 4-[tert-Butylamino-(dimethoxy-phosphoryl)-methyl]-benzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[tert-Butylamino-(dimethoxy-phosphoryl)-methyl]-benzoic acid

There total 1 articles about 4-[tert-Butylamino-(dimethoxy-phosphoryl)-methyl]-benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

Dimethyl phosphite (868-85-9) + 4-[(E)-tert-Butylimino-methyl]-benzoic acid → 4-[tert-Butylamino-(dimethoxy-phosphoryl)-methyl]-benzoic acid (176903-54-1)

Guidance literature:

With sodium hydride; In 1,4-dioxane; ethanol;

Reference yield: 88.0%

4-[tert-Butylamino-(dimethoxy-phosphoryl)-methyl]-benzoic acid (176903-54-1) → 4-(tert-Butylamino-phosphono-methyl)-benzoic acid

Guidance literature:

With hydrogen bromide; In 1,4-dioxane; for 2h; Heating;

Reference yield:

isopropylamine (75-31-0) + 4-[tert-Butylamino-(dimethoxy-phosphoryl)-methyl]-benzoic acid (176903-54-1) → 4-[tert-butylamino-(dimethoxy-phosphoryl)-methyl]-benzoic acid; compound with isopropylamine

Guidance literature:

In methanol;

DOI:10.1080/10426509608046392

upstream raw materials:

Dimethyl phosphite