2-amino-N-(4-bromophenyl)acetamide

Base Information

Chemical Name:2-amino-N-(4-bromophenyl)acetamide
CAS No.:325852-86-6
Molecular Formula:C₈H₉BrN₂O
Molecular Weight:229.076
Hs Code.:
DSSTox Substance ID:DTXSID301320274
ChEMBL ID:CHEMBL1708720

Synonyms:N1-(4-Bromophenyl)glycinamide;2-amino-N-(4-bromophenyl)acetamide;325852-86-6;Cambridge id 5540904;N-(4-bromophenyl)glycinamide;MLS000624486;SCHEMBL7445670;CHEMBL1708720;DTXSID301320274;HMS1582F17;HMS2733E08;STL197526;AKOS000172618;SMR000323437;EN300-58339;AB00088125-01;SR-01000212156;SR-01000212156-1;F0814-0010

Suppliers and Price of 2-amino-N-(4-bromophenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-amino-N-(4-bromophenyl)acetamide

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:227.98983
Heavy Atom Count:12
Complexity:155

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1NC(=O)CN)Br

Technology Process of 2-amino-N-(4-bromophenyl)acetamide

There total 2 articles about 2-amino-N-(4-bromophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 2564-02-5
N-(4-bromophenyl)-2-chloroacetamide

: 325852-86-6
2-amino-N-(4-bromophenyl)acetamide

Guidance literature:: With ammonium hydroxide; at 60 ℃; for 6h; Inert atmosphere;
DOI:10.1016/j.ejmech.2020.112257

Reference yield:

: 106-40-1
4-bromo-aniline

: 325852-86-6
2-amino-N-(4-bromophenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; dmap / dichloromethane / 5 h / 20 °C

2: trifluoroacetic acid / dichloromethane / 24 h / 20 °C

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.bmcl.2014.07.003

Reference yield: 85.0%

: 325852-86-6
2-amino-N-(4-bromophenyl)acetamide

: 3-methyl-2-(phenylsulphonamido)pentanoic acid

: N-(2-(4-bromophenylamino)?2-oxoethyl)?3-methyl-2-(phenylsulfonamido)pentanamide

Guidance literature:: 3-methyl-2-(phenylsulphonamido)pentanoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 0 - 20 ℃; for 8.16667h;

2-amino-N-(4-bromophenyl)acetamide; In dichloromethane; at 20 ℃; for 16h;
DOI:10.1016/j.molstruc.2021.130017