(S)-2-Amino-4-methyl-pentanoic acid [2-(1H-benzoimidazol-2-ylsulfanyl)-phenyl]-amide

Base Information

Chemical Name:(S)-2-Amino-4-methyl-pentanoic acid [2-(1H-benzoimidazol-2-ylsulfanyl)-phenyl]-amide
CAS No.:135430-31-8
Molecular Formula:C₁₉H₂₂N₄OS
Molecular Weight:354.476
Hs Code.:

Synonyms:(S)-2-Amino-4-methyl-pentanoic acid [2-(1H-benzoimidazol-2-ylsulfanyl)-phenyl]-amide

Suppliers and Price of (S)-2-Amino-4-methyl-pentanoic acid [2-(1H-benzoimidazol-2-ylsulfanyl)-phenyl]-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-Amino-4-methyl-pentanoic acid [2-(1H-benzoimidazol-2-ylsulfanyl)-phenyl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-Amino-4-methyl-pentanoic acid [2-(1H-benzoimidazol-2-ylsulfanyl)-phenyl]-amide

There total 7 articles about (S)-2-Amino-4-methyl-pentanoic acid [2-(1H-benzoimidazol-2-ylsulfanyl)-phenyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.3%

: 135430-23-8
{(S)-1-[2-(1H-Benzoimidazol-2-ylsulfanyl)-phenylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester

: 135430-31-8
(S)-2-Amino-4-methyl-pentanoic acid [2-(1H-benzoimidazol-2-ylsulfanyl)-phenyl]-amide

Guidance literature:: With hydrogen bromide; acetic acid; for 2h; Ambient temperature;
DOI:10.1016/0223-5234(91)90024-H

Reference yield:

: 137-07-5
2-amino-benzenethiol

: 135430-31-8
(S)-2-Amino-4-methyl-pentanoic acid [2-(1H-benzoimidazol-2-ylsulfanyl)-phenyl]-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 52 percent / Et₃N / dimethylformamide; CHCl₃ / 2 h / Heating

2: 85.7 percent / hexamethylphosphoric acid triamide; acetonitrile / 4 h / Ambient temperature

3: 89.3 percent / 30percent HBr-AcOH / 2 h / Ambient temperature

With hydrogen bromide; acetic acid; triethylamine; In N,N,N,N,N,N-hexamethylphosphoric triamide; chloroform; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/0223-5234(91)90024-H

Reference yield:

: 4857-06-1
2-chloro-1H-benzoimidazole

: 135430-31-8
(S)-2-Amino-4-methyl-pentanoic acid [2-(1H-benzoimidazol-2-ylsulfanyl)-phenyl]-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 52 percent / Et₃N / dimethylformamide; CHCl₃ / 2 h / Heating

2: 85.7 percent / hexamethylphosphoric acid triamide; acetonitrile / 4 h / Ambient temperature

3: 89.3 percent / 30percent HBr-AcOH / 2 h / Ambient temperature

With hydrogen bromide; acetic acid; triethylamine; In N,N,N,N,N,N-hexamethylphosphoric triamide; chloroform; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/0223-5234(91)90024-H