Carbonic acid (R)-5,5-bis-benzenesulfonyl-6-methyl-oct-7-en-2-ynyl ester methyl ester

Base Information

• Chemical Name: Carbonic acid (R)-5,5-bis-benzenesulfonyl-6-methyl-oct-7-en-2-ynyl ester methyl ester
• CAS No.: 191861-57-1
• Molecular Formula: C₂₃H₂₄O₇S₂
• Molecular Weight: 476.571
• Mol file: 191861-57-1.mol

Synonyms:Carbonic acid (R)-5,5-bis-benzenesulfonyl-6-methyl-oct-7-en-2-ynyl ester methyl ester

Chemical Property of Carbonic acid (R)-5,5-bis-benzenesulfonyl-6-methyl-oct-7-en-2-ynyl ester methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbonic acid (R)-5,5-bis-benzenesulfonyl-6-methyl-oct-7-en-2-ynyl ester methyl ester

There total 2 articles about Carbonic acid (R)-5,5-bis-benzenesulfonyl-6-methyl-oct-7-en-2-ynyl ester methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-bromobut-2-ynyl methyl carbonate + (3R)-4,4-bis(phenylsulfonyl)-3-methylbut-1-ene (191861-56-0) → Carbonic acid (R)-5,5-bis-benzenesulfonyl-6-methyl-oct-7-en-2-ynyl ester methyl ester (191861-57-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 16h;

DOI:10.1002/hlca.19970800302

Reference yield:

((E)-(R)-4,4-Bis-benzenesulfonyl-3-methyl-but-1-enyl)-trimethyl-silane (191861-55-9) → Carbonic acid (R)-5,5-bis-benzenesulfonyl-6-methyl-oct-7-en-2-ynyl ester methyl ester (191861-57-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / TsOH*H₂O / acetonitrile / 5 h / Heating

2: 88 percent / K₂CO₃ / dimethylformamide / 16 h / 60 °C

With potassium carbonate; toluene-4-sulfonic acid; In N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/hlca.19970800302

Reference yield: 91.0%

dimethyl zinc(II) (544-97-8) + Carbonic acid (R)-5,5-bis-benzenesulfonyl-6-methyl-oct-7-en-2-ynyl ester methyl ester (191861-57-1) → (1R,4R,5R)-3,3-Bis-benzenesulfonyl-1-isopropenyl-4-methyl-bicyclo[3.1.0]hexane (191861-58-2)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; trifuran-2-yl-phosphane; In diethyl ether; toluene; at 34 ℃; for 4h;

DOI:10.1002/hlca.19970800302

upstream raw materials:

(3R)-4,4-bis(phenylsulfonyl)-3-methylbut-1-ene

((E)-(R)-4,4-Bis-benzenesulfonyl-3-methyl-but-1-enyl)-trimethyl-silane

Downstream raw materials:

(1R,4R,5R)-3,3-Bis-benzenesulfonyl-1-isopropenyl-4-methyl-bicyclo[3.1.0]hexane

(-)-α-thujone

(1S,4R,5R)-3-Benzenesulfonyl-1-isopropyl-4-methyl-bicyclo[3.1.0]hexane

(1S,4R,5R)-3,3-Bis-benzenesulfonyl-1-isopropyl-4-methyl-bicyclo[3.1.0]hexane