NSCI

Base Information

Chemical Name:NSCI
CAS No.:220510-16-7
Molecular Formula:C26H24 N2 O5 S
Molecular Weight:476.553
Hs Code.:
Mol file:220510-16-7.mol

Synonyms:Pyrrolidine,1-[[2,3-dihydro-2,3-dioxo-1-(phenylmethyl)-1H-indol-5-yl]sulfonyl]-2-(phenoxymethyl)-,(2S)- (9CI)

Suppliers and Price of NSCI

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
NSCI ≥97% (HPLC), solid
25 mg
$ 732.00

Sigma-Aldrich
NSCI ≥97% (HPLC), solid
5 mg
$ 201.00

Total 0 raw suppliers

Chemical Property of NSCI

Chemical Property:

PSA：92.37000
LogP:4.73190
Storage Temp.:−20°C

Purity/Quality:: NSCI ≥97% (HPLC), solid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of NSCI

There total 7 articles about NSCI which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 100-39-0
benzyl bromide

: 220509-98-8
5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione

: 220510-16-7
(S)-1-benzyl-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)isatin

Guidance literature:: 5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h;

benzyl bromide; In N,N-dimethyl-formamide; Further stages.;
DOI:10.1021/jm0100537

Reference yield: 64.0%

: 220510-16-7
(S)-1-benzyl-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)isatin

Guidance literature:

Reference yield:

: 132898-96-5
5-chlorosulfonylisatin

: 220510-16-7
(S)-1-benzyl-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)isatin

Guidance literature:: Multi-step reaction with 2 steps

1.1: TFA / CH₂Cl₂

1.2: Et₃N / CH₂Cl₂

2.1: NaH / dimethylformamide / 0 °C

2.2: dimethylformamide / 20 °C

With sodium hydride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm070506t