(2R,3R)-cis-1-(N-1-bis(2-methylphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

Base Information

Chemical Name:(2R,3R)-cis-1-(N-1-bis(2-methylphenyl)methyl)-2-carboxyethyl-3-phenylaziridine
CAS No.:1072879-73-2
Molecular Formula:C₂₆H₂₇NO₂
Molecular Weight:385.506
Hs Code.:

Synonyms:(2R,3R)-cis-1-(N-1-bis(2-methylphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3R)-cis-1-(N-1-bis(2-methylphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

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Technology Process of (2R,3R)-cis-1-(N-1-bis(2-methylphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

There total 2 articles about (2R,3R)-cis-1-(N-1-bis(2-methylphenyl)methyl)-2-carboxyethyl-3-phenylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 623-73-4
diazoacetic acid ethyl ester

: 1072879-59-4
N-benzylidene-bis(2-methylphenyl)methylamine

: 1072879-73-2
(2R,3R)-cis-1-(N-1-bis(2-methylphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

Guidance literature:: N-benzylidene-bis(2-methylphenyl)methylamine; With triphenylborane; (3S)-(+)-2,2'-diphenyl-(3,3'-biphenanthrene)-4,4'-diol; In tetrachloromethane; at 25 ℃; for 0.0833333h; Inert atmosphere;

diazoacetic acid ethyl ester; In tetrachloromethane; at 25 ℃; for 24h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol802431v

Reference yield:

: 623-73-4
diazoacetic acid ethyl ester

: 1072879-59-4
N-benzylidene-bis(2-methylphenyl)methylamine

: 1072879-73-2
(2R,3R)-cis-1-(N-1-bis(2-methylphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

: (2S,3S)-cis-1-(N-1-bis(2-methylphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

Guidance literature:: N-benzylidene-bis(2-methylphenyl)methylamine; With triphenylborane; (3S)-(+)-2,2'-diphenyl-(3,3'-biphenanthrene)-4,4'-diol; In dichloromethane; at 25 ℃; for 0.0833333h; Inert atmosphere;

diazoacetic acid ethyl ester; In dichloromethane; at 25 ℃; for 24h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol802431v