2-(3-Bromophenyl)-4-chloropyrimidine

Base Information

Chemical Name:2-(3-Bromophenyl)-4-chloropyrimidine
CAS No.:97604-15-4
Molecular Formula:C₁₀H₆BrClN₂
Molecular Weight:269.528
Hs Code.:
European Community (EC) Number:961-218-8

Synonyms:2-(3-bromophenyl)-4-chloropyrimidine;97604-15-4;MFCD11043798;AKOS009845226;EN300-705984;G55827;Z445153136

Suppliers and Price of 2-(3-Bromophenyl)-4-chloropyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-(3-Bromophenyl)-4-chloropyrimidine

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:267.94029
Heavy Atom Count:14
Complexity:191

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Br)C2=NC=CC(=N2)Cl

Technology Process of 2-(3-Bromophenyl)-4-chloropyrimidine

There total 3 articles about 2-(3-Bromophenyl)-4-chloropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 97604-03-0
2-(3-bromophenyl)-4(1H)-pyrimidinone

: 97604-15-4
2-(3-Bromo-phenyl)-4-chloro-pyrimidine

Guidance literature:: With trichlorophosphate; for 3h; Heating;
DOI:10.1021/jm00166a023

Reference yield:

: 6952-59-6
3-cyanobromobenzene

: 97604-15-4
2-(3-Bromo-phenyl)-4-chloro-pyrimidine

Guidance literature:: Multi-step reaction with 4 steps

1: HCl (gas) / diethyl ether / 3 - 4 °C

2: NH₃ (gas) / ethanol / 96 h / 0 °C

3: KOH / ethanol / 2.5 h / Heating

4: 53 percent / POCl₃ / 3 h / Heating

With hydrogenchloride; potassium hydroxide; ammonia; trichlorophosphate; In diethyl ether; ethanol;
DOI:10.1021/jm00166a023

Reference yield:

: 16796-52-4
3-bromobenzene-1-carboximidamide hydrochloride

: 97604-15-4
2-(3-Bromo-phenyl)-4-chloro-pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / ethanol / 2.5 h / Heating

2: 53 percent / POCl₃ / 3 h / Heating

With potassium hydroxide; trichlorophosphate; In ethanol;
DOI:10.1021/jm00166a023