(R)-(+)-2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol

Base Information

• Chemical Name: (R)-(+)-2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol
• CAS No.: 210295-65-1
• Molecular Formula: C₁₈H₂₀O₂
• Molecular Weight: 268.356
• Mol file: 210295-65-1.mol

Synonyms:(R)-(+)-2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol

Chemical Property of (R)-(+)-2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-(+)-2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol

There total 5 articles about (R)-(+)-2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ (R)-(+)-2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol (210295-65-1)

Guidance literature:

Reference yield:

Butyric acid (R)-3-(4-butyryloxy-phenyl)-1,1,3-trimethyl-indan-5-yl ester (251450-95-0) → (R)-(+)-2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol (210295-65-1)

Guidance literature:

With potassium hydroxide; In methanol; at 20 ℃; for 1h;

DOI:10.1021/jo005681v

Reference yield:

butyric acid 3-(4-butyryloxy-phenyl)-1,1,3-trimethyl-indan-5-yl ester (223791-49-9) → (R)-(+)-2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol (210295-65-1) + Butyric acid 4-((R)-6-hydroxy-1,3,3-trimethyl-indan-1-yl)-phenyl ester + Butyric acid 4-((S)-6-hydroxy-1,3,3-trimethyl-indan-1-yl)-phenyl ester (223791-50-2)

Guidance literature:

butyric acid 3-(4-butyryloxy-phenyl)-1,1,3-trimethyl-indan-5-yl ester; With sodium hydroxide; phosphate buffer; Chromobacterium Viscosum lipase; for 5h; pH=7.2;

With sodium methylate; In methanol; at 20 ℃; for 2h;

DOI:10.1021/jo990795w

upstream raw materials:

pentanoic acid 1,1,3-trimethyl-3-(4-pentanoyloxy-phenyl)-indan-5-yl ester

butyric acid 3-(4-butyryloxy-phenyl)-1,1,3-trimethyl-indan-5-yl ester

Butyric acid (R)-3-(4-butyryloxy-phenyl)-1,1,3-trimethyl-indan-5-yl ester

5-hydroxy-3-(4-hydroxyphenyl)-1,1,3-trimethylindane