1,3-Bis[bis(3,5-dimethylphenyl)phosphino]propane

Base Information

Chemical Name:1,3-Bis[bis(3,5-dimethylphenyl)phosphino]propane
CAS No.:220185-36-4
Molecular Formula:C35H42 P2
Molecular Weight:524.666
Hs Code.:
DSSTox Substance ID:DTXSID20400568
Wikidata:Q82203579
Mol file:220185-36-4.mol

Synonyms:1,3-BIS[BIS(3,5-DIMETHYLPHENYL)PHOSPHINO]PROPANE;220185-36-4;3-bis(3,5-dimethylphenyl)phosphanylpropyl-bis(3,5-dimethylphenyl)phosphane;1,3-Bis(bis(3,5-dimethylphenyl)phosphino)propane;SCHEMBL2228016;DTXSID20400568;FT-0760497

Suppliers and Price of 1,3-Bis[bis(3,5-dimethylphenyl)phosphino]propane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,3-BIS[BIS(3,5-DIMETHYLPHENYL)PHOSPHINO]PROPANE 95.00%
5MG
$ 504.26

Total 4 raw suppliers

Chemical Property of 1,3-Bis[bis(3,5-dimethylphenyl)phosphino]propane

Chemical Property:

PSA：27.18000
LogP:8.10950
XLogP3:9.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:8
Exact Mass:524.27617534
Heavy Atom Count:37
Complexity:528

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,3-BIS[BIS(3,5-DIMETHYLPHENYL)PHOSPHINO]PROPANE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1)P(CCCP(C2=CC(=CC(=C2)C)C)C3=CC(=CC(=C3)C)C)C4=CC(=CC(=C4)C)C)C

Technology Process of 1,3-Bis[bis(3,5-dimethylphenyl)phosphino]propane

There total 4 articles about 1,3-Bis[bis(3,5-dimethylphenyl)phosphino]propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: propane-1,3-diylbis[bis(3,5-dimethylphenyl)phosphine oxide]

: 220185-36-4
1,3-bis(bis(3,5-dimethylphenyl)phosphino)propane

Guidance literature:: propane-1,3-diylbis[bis(3,5-dimethylphenyl)phosphine oxide]; With cerium(III) chloride; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 16h; Inert atmosphere;
DOI:10.1246/bcsj.20210023

Reference yield: 48.0%

: 28240-70-2
1,3-Propandiylbis(dichlorphosphan)

: 34696-73-6
3,5-dimethyphenylmagnesium bromide

: 220185-36-4
1,3-bis(bis(3,5-dimethylphenyl)phosphino)propane

Guidance literature:: In tetrahydrofuran; at -78 ℃; for 0.5h;
DOI:10.1021/om500518r

Reference yield:

: 187344-92-9
bis(3,5-dimethylphenyl)phosphine oxide

: 220185-36-4
1,3-bis(bis(3,5-dimethylphenyl)phosphino)propane

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; paraffin oil / 0.67 h / 20 °C / Inert atmosphere

1.2: 16 h / Inert atmosphere

2.1: cerium(III) chloride / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere

2.2: 16 h / 0 - 20 °C / Inert atmosphere

With cerium(III) chloride; sodium hydride; In tetrahydrofuran; paraffin oil;
DOI:10.1246/bcsj.20210023