3-(1H-indol-3-yl)propanehydrazide

Base Information

• Chemical Name: 3-(1H-indol-3-yl)propanehydrazide
• CAS No.: 20401-90-5
• Molecular Formula: C11H13 N3 O
• Molecular Weight: 203.244

Synonyms:Indole-3-propionicacid, hydrazide (7CI,8CI); 1H-Indole-3-propionic acid hydrazide;3-(1H-Indol-3-yl)propanoic hydrazide; NSC 25649

Chemical Property of 3-(1H-indol-3-yl)propanehydrazide

Chemical Property:

• Vapor Pressure: 8.59E-11mmHg at 25°C
• Boiling Point: 516.9°Cat760mmHg
• Flash Point: 266.4°C
• Density: 1.263g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(1H-indol-3-yl)propanehydrazide

There total 5 articles about 3-(1H-indol-3-yl)propanehydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

ethyl 3-(indol-3-yl)propanoate (40641-03-0) → 3-(1H-indol-3-yl)propanehydrazide (20401-90-5)

Guidance literature:

With ethanol; hydrazine; at 60 ℃;

Reference yield: 92.0%

Methyl indole-3-propionate (5548-09-4) → 3-(1H-indol-3-yl)propanehydrazide (20401-90-5)

Guidance literature:

With hydrazine hydrate; Microwave irradiation;

DOI:10.3184/174751915X14306656265736

Reference yield: 92.0%

→ 3-(1H-indol-3-yl)propanehydrazide (20401-90-5)

Guidance literature:

With hydrazine hydrate; Reflux; Microwave irradiation;

upstream raw materials:

Methyl indole-3-propionate

Indole-3-propionic acid

ethyl 3-(indol-3-yl)propanoate

Downstream raw materials:

tert-butyl (R)-1-(5-(2-(1H-indol-3-yl)ethyl)-4-(2,4-dimethoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethylcarbamate

C₃₆H₄₀N₆O₄

C₃₅H₃₈N₆O₃

(R)-tert-butyl 1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethylcarbamate

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