methyl 2-bromo-6-(3'-methoxyphenylamino)isonicotinamide

Base Information

• Chemical Name: methyl 2-bromo-6-(3'-methoxyphenylamino)isonicotinamide
• CAS No.: 1092771-12-4
• Molecular Formula: C₁₄H₁₃BrN₂O₃
• Molecular Weight: 337.173
• Mol file: 1092771-12-4.mol

Synonyms:methyl 2-bromo-6-(3'-methoxyphenylamino)isonicotinamide

Chemical Property of methyl 2-bromo-6-(3'-methoxyphenylamino)isonicotinamide

Chemical Property:

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Technology Process of methyl 2-bromo-6-(3'-methoxyphenylamino)isonicotinamide

There total 1 articles about methyl 2-bromo-6-(3'-methoxyphenylamino)isonicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

m-Anisidine (536-90-3,918666-97-4) + methyl 2,6-dibromoisonicotinate (119308-57-5) → methyl 2-bromo-6-(3'-methoxyphenylamino)isonicotinamide (1092771-12-4)

Guidance literature:

With palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 90 ℃; for 46h; Inert atmosphere;

DOI:10.1055/s-2008-1067208

upstream raw materials:

m-Anisidine

methyl 2,6-dibromoisonicotinate