Technology Process of (Z)-1-(p-tolyl)ethanone O-benzyloxime
There total 4 articles about (Z)-1-(p-tolyl)ethanone O-benzyloxime which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(Z)-1-(p-tolyl)ethanone oxime;
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 1h;
benzyl bromide;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 18h;
DOI:10.1021/jo400371x
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: bromine / dichloromethane / 1 h / 0 °C
2.1: hydroxylamine hydrochloride / water; methanol / 25 °C
3.1: sodium tetrahydroborate / water; acetonitrile / 0.17 h / 25 °C
4.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C
4.2: 18 h / 20 °C
With
sodium tetrahydroborate; hydroxylamine hydrochloride; bromine; sodium hydride;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo400371x
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydroxylamine hydrochloride / water; methanol / 25 °C
2.1: sodium tetrahydroborate / water; acetonitrile / 0.17 h / 25 °C
3.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C
3.2: 18 h / 20 °C
With
sodium tetrahydroborate; hydroxylamine hydrochloride; sodium hydride;
In
methanol; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo400371x
