1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide

Base Information

Chemical Name:1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide
CAS No.:1031289-51-6
Molecular Formula:C₁₉H₂₀F₃N₃O₃
Molecular Weight:395.381
Hs Code.:

Synonyms:1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide

Suppliers and Price of 1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide

Chemical Property:

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Technology Process of 1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide

There total 2 articles about 1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1031289-49-2
N-(1,4-dioxaspiro[4.5]dec-8-yl)-1-methyl-N-[3-trifluoromethoxybenzyl]-1H-imidazole-4-carboxamide

: 1031289-51-6
1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide

Guidance literature:: N-(1,4-dioxaspiro[4.5]dec-8-yl)-1-methyl-N-[3-trifluoromethoxybenzyl]-1H-imidazole-4-carboxamide; With hydrogenchloride; In tetrahydrofuran; water; at 70 ℃; for 96h;

With potassium carbonate; In tetrahydrofuran; water; Product distribution / selectivity;

Reference yield:

: 1031289-55-0
4-{[3-(trifluoromethoxy)benzyl]amino}cyclohexanone

: 143165-09-7
1-methyl-1H-imidazole-4-carbonyl chloride

: 1031289-51-6
1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide

Guidance literature:: With base; Product distribution / selectivity;

Reference yield:

: 1031289-51-6
1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide

: 78797-58-7,78797-59-8,78797-62-3,36520-39-5,65546-09-0
azetidine hydrochloride

: 1031310-34-5
C₂₂H₂₇F₃N₄O₂

: 1031289-53-8
1-methyl-N-(cis-4-azetidin-4-ylcyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide

Guidance literature:: 1-methyl-N-(4-oxocyclohexyl)-N-[3-(trifluoromethoxy)benzyl]-1H-imidazole-4-carboxamide; azetidine hydrochloride; With triethylamine; In dichloromethane; for 0.333333h;

With sodium tris(acetoxy)borohydride; In dichloromethane; at 20 ℃; for 6h;