alpha-(4-Methyl-3-penten-1-yn-1-yl)benzenemethanol

Base Information

Chemical Name:alpha-(4-Methyl-3-penten-1-yn-1-yl)benzenemethanol
CAS No.:1791-19-1
Molecular Formula:C₁₃H₁₄O
Molecular Weight:186.254
Hs Code.:
DSSTox Substance ID:DTXSID201245500

Synonyms:alpha-(4-Methyl-3-penten-1-yn-1-yl)benzenemethanol;DTXSID201245500;1791-19-1

Suppliers and Price of alpha-(4-Methyl-3-penten-1-yn-1-yl)benzenemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of alpha-(4-Methyl-3-penten-1-yn-1-yl)benzenemethanol

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:186.104465066
Heavy Atom Count:14
Complexity:254

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=CC#CC(C1=CC=CC=C1)O)C

Technology Process of alpha-(4-Methyl-3-penten-1-yn-1-yl)benzenemethanol

There total 3 articles about alpha-(4-Methyl-3-penten-1-yn-1-yl)benzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 64305-70-0
1,1-dibromo-4-methyl-1,3-pentadiene

: 100-52-7
benzaldehyde

: 1791-19-1
5-methyl-1-phenylhex-4-en-2-yn-1-ol

Guidance literature:: 1,1-dibromo-4-methyl-1,3-pentadiene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 0.666667h; Inert atmosphere;

benzaldehyde; In tetrahydrofuran; at -78 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.orglett.1c01987

Reference yield:

: 590-37-4
2-methylpent-4-yn-2-ol

: 1791-19-1
5-methyl-1-phenylhex-4-en-2-yn-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: TsCl, Py

2: (i) EtMgBr, Et₂O, (ii) /BRN= 471223/

With pyridine; p-toluenesulfonyl chloride;