4-ISOPROPOXY-2-BUTANONE

Base Information

• Chemical Name: 4-ISOPROPOXY-2-BUTANONE
• CAS No.: 32541-58-5
• Molecular Formula: C7H14 O2
• Molecular Weight: 130.187
• Hs Code.: 2914509090
• Mol file: 32541-58-5.mol

Synonyms:2-Butanone,4-isopropoxy- (7CI,8CI); 4-(2-Propoxy)-2-butanone; 4-Isopropoxy-2-butanone

Chemical Property of 4-ISOPROPOXY-2-BUTANONE

Chemical Property:

• Vapor Pressure: 1.71mmHg at 25°C
• Refractive Index: 1.404
• Boiling Point: 75 °C / 35mmHg
• Flash Point: 46.7°C
• PSA: 26.30000
• Density: 0,89 g/cm3
• LogP: 1.39050

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Isopropoxy-2-butanone ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-ISOPROPOXY-2-BUTANONE

There total 6 articles about 4-ISOPROPOXY-2-BUTANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

methyl vinyl ketone (78-94-4,25038-87-3) + isopropyl alcohol (67-63-0,8013-70-5) → 4-isopropoxy-2-butanone (32541-58-5)

Guidance literature:

With trimethylphosphane; In acetonitrile; at 20 ℃; for 1h;

DOI:10.1021/ja035232n

Reference yield:

6-methylhept-5-en-2-ol (4630-06-2,1569-60-4) + sulfuric acid (7664-93-9) + methyl vinyl ketone (78-94-4,25038-87-3) → 4-isopropoxy-2-butanone (32541-58-5)

Guidance literature:

With potassium carbonate; In water; isopropyl alcohol;

Reference yield:

sulfuric acid (7664-93-9) + methyl vinyl ketone (78-94-4,25038-87-3) → 4-isopropoxy-2-butanone (32541-58-5)

Guidance literature:

With potassium carbonate; In water; isopropyl alcohol;

upstream raw materials:

methyl vinyl ketone

isopropyl alcohol

3-buten-1-yne

1-[2-(2,4-Dimethyl-[1,3]dioxolan-2-yl)-ethoxy]-propan-2-ol

Downstream raw materials:

methyl vinyl ketone

4-isopropoxy-2-butanol

Refernces

• 1、 Espinosa, Antonio,Gallo, Miguel A.,Campos, Joaquin,Enterna, Antonio,Camacho, Encarnacion. "Carbon-13 NMR Spectra of 1,3-Dioxolanes. II - Determination of α, β and γ Parameters for 2- and 4-Methyl Groups in Stereoisomeric Derivatives by the Pattern Molecule Method". . p. 108 - 110. Retrieved 1988.
• 2、 Gutiérrez, Rsuini U.,Rebollar, Araceli,Bautista, Rafael,Pelayo, Vanessa,Várgas, José Luis,Montenegro, Mabel M.,Espinoza-Hicks, Carlos,Ayala, Francisco,Bernal, Pablo M.,Carrasco, Cuauhtemoc,Zepeda, L. Gerardo,Delgado, Francisco,Tamariz, Joaquín. "Functionalized α-oximinoketones as building blocks for the construction of imidazoline-based potential chiral auxiliaries". . p. 230 - 246. Retrieved 2015/03/04.