Carbamic acid, [(methylsulfonyl)oxy]-, 1,1-dimethylethyl ester (9CI)

Base Information

• Chemical Name: Carbamic acid, [(methylsulfonyl)oxy]-, 1,1-dimethylethyl ester (9CI)
• CAS No.: 219844-41-4
• Molecular Formula: C6H13 N O5 S
• Molecular Weight: 211.23612
• Mol file: 219844-41-4.mol

Synonyms:Carbamicacid, [(methylsulfonyl)oxy]-, 1,1-dimethylethyl ester (9CI)

Chemical Property of Carbamic acid, [(methylsulfonyl)oxy]-, 1,1-dimethylethyl ester (9CI)

Chemical Property:

• PSA: 90.08000
• LogP: 1.87400

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbamic acid, [(methylsulfonyl)oxy]-, 1,1-dimethylethyl ester (9CI)

There total 1 articles about Carbamic acid, [(methylsulfonyl)oxy]-, 1,1-dimethylethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

tert-Butyl N-hydroxycarbamate (36016-38-3) + methanesulfonyl chloride (124-63-0) → N-tert-butyloxycarbonyl-O-methanesulfonylhydroxylamine (219844-41-4)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jo301372y

Reference yield: 97.0%

(S)-(+)-4-phenylpentan-1-ol + N-tert-butyloxycarbonyl-O-methanesulfonylhydroxylamine (219844-41-4) → tert-butyl (S)-(methylsulfonyloxy)(4-phenylpentyl)carbamate

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 20h; Inert atmosphere;

DOI:10.1021/jacs.7b09901

Reference yield: 87.0%

hydrocinnamic acid chloride (645-45-4) + N-tert-butyloxycarbonyl-O-methanesulfonylhydroxylamine (219844-41-4) → N-(t-butyloxycarbonyl)-N-(methanesulfonyloxy)-3-phenylpropionamide (219844-52-7)

Guidance literature:

With dmap; triethylamine; In N,N-dimethyl-formamide; 0 deg C to rt;

DOI:10.1021/jo981498e

upstream raw materials:

tert-Butyl N-hydroxycarbamate

methanesulfonyl chloride

Downstream raw materials:

N-(t-butyloxycarbonyl)-N-(methanesulfonyloxy)-3-phenylpropionamide