C₅₇H₆₆O₉

Base Information

• Chemical Name: C₅₇H₆₆O₉
• CAS No.: 364068-95-1
• Molecular Formula: C₅₇H₆₆O₉
• Molecular Weight: 895.146
• Mol file: 364068-95-1.mol

Synonyms:C₅₇H₆₆O₉

Chemical Property of C₅₇H₆₆O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₇H₆₆O₉

There total 11 articles about C₅₇H₆₆O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

carbonic acid tert-butyl ester 2-iodophenyl ester (364068-85-9) + C46H54O6 (364068-94-0) → C57H66O9 (364068-95-1)

Guidance literature:

With copper(l) iodide; triethylamine; triphenylphosphine; palladium diacetate; at 70 ℃; for 6h;

DOI:10.1002/chem.200305284

Reference yield:

2-hexylphenol (3226-32-2) → C57H66O9 (364068-95-1)

Guidance literature:

Multi-step reaction with 8 steps

1: 17.3 g / iodine monochloride; Et₃N / CH₂Cl₂ / 3.5 h / 0 °C

2: 85 percent / Et₃N; DMAP / CH₂Cl₂ / 1 h / 0 °C

3: 69 percent / CuI; PPh₃; Et₃N / Pd(OAc)2 / 72 h / 20 °C

4: NaOH / methanol; tetrahydrofuran / 20 °C

5: 5.4 g / K₂CO₃; DMAP; [18]crown-6 / tetrahydrofuran / 1 h

6: CuI; PPh₃; Et₃N / Pd(OAc)2 / 6 h / 70 °C

7: 1.96 g / tetrabutylammonium fluoride / CH₂Cl₂; tetrahydrofuran

8: 92 percent / CuI; PPh₃; Et₃N / Pd(OAc)2 / 6 h / 70 °C

With dmap; sodium hydroxide; copper(l) iodide; 18-crown-6 ether; tetrabutyl ammonium fluoride; Iodine monochloride; potassium carbonate; triethylamine; triphenylphosphine; palladium diacetate; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1002/chem.200305284

Reference yield:

2-n-hexyl-1-methoxybenzene (81693-79-0) → C57H66O9 (364068-95-1)

Guidance literature:

Multi-step reaction with 9 steps

1: boron tribromide / CH₂Cl₂

2: 17.3 g / iodine monochloride; Et₃N / CH₂Cl₂ / 3.5 h / 0 °C

3: 85 percent / Et₃N; DMAP / CH₂Cl₂ / 1 h / 0 °C

4: 69 percent / CuI; PPh₃; Et₃N / Pd(OAc)2 / 72 h / 20 °C

5: NaOH / methanol; tetrahydrofuran / 20 °C

6: 5.4 g / K₂CO₃; DMAP; [18]crown-6 / tetrahydrofuran / 1 h

7: CuI; PPh₃; Et₃N / Pd(OAc)2 / 6 h / 70 °C

8: 1.96 g / tetrabutylammonium fluoride / CH₂Cl₂; tetrahydrofuran

9: 92 percent / CuI; PPh₃; Et₃N / Pd(OAc)2 / 6 h / 70 °C

With dmap; sodium hydroxide; copper(l) iodide; 18-crown-6 ether; tetrabutyl ammonium fluoride; Iodine monochloride; boron tribromide; potassium carbonate; triethylamine; triphenylphosphine; palladium diacetate; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1002/chem.200305284

upstream raw materials:

carbonic acid tert-butyl ester 2-iodophenyl ester

C₄₆H₅₄O₆

2-hexylphenol

2-n-hexyl-1-methoxybenzene

Refernces