3226-32-2Relevant articles and documents
Dearomatization-Rearomatization Strategy for ortho-Selective Alkylation of Phenols with Primary Alcohols
Yu, Jianjin,Li, Chao-Jun,Zeng, Huiying
supporting information, p. 4043 - 4048 (2020/12/18)
Phenols are common precursors and core structures of a variety of industrial chemicals ranging from pharmaceuticals to polymers. However, the synthesis of site-specifically substituted phenols is challenging, and thus the development of new methods for this purpose would be highly desirable. Reported here is a protocol for palladium-catalyzed ortho-selective alkylation reactions of phenols with primary alcohols by a dearomatization-rearomatization strategy, with water as the sole by-product. Various substituted phenols and primary alcohols were compatible with the standard reaction conditions. The detailed mechanism of this transformation was also investigated.
Preparation method of ortho-alkylphenol
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Paragraph 0007; 0010, (2019/01/14)
The invention relates to a preparation method of ortho-alkylphenol. A 2-(2-alkylphenoxy) pyridine derivative is used as a raw material to prepare the ortho-alkylphenol. The reaction process includes:directly adding the 2-(2-alkylphenoxy) pyridine derivati
Photochemistry of 3-substituted bicyclo[3.1.0]hex-3-en-2-ones. Regioselective synthesis of ortho-substituted phenols by Pauson-Khand reaction
Marchueta, Iolanda,Olivella, Santiago,Sola, Lluis,Moyano, Albert,Pericas, Miquel A.,Riera, Antoni
, p. 3197 - 3200 (2007/10/03)
(equation presented) 3-Substituted bicyclo[3.1.0]hex-3-en-2-ones 3, easily obtained by Pauson-Khand reaction between terminal alkynes and cyclopropene, have been quantitatively converted into ortho-substituted phenols 4 by irradiation with UV light (350 n