Technology Process of C24H22N2O5
There total 3 articles about C24H22N2O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
3-(2,5-dimethyl-1H-pyrrol-1-yl)-4-(methoxycarbonyl)benzoic acid;
With
N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 1h;
Sealed tube;
1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid hydrochloride;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 3h;
Sealed tube;
With
water; sodium hydroxide;
In
methanol;
at 60 ℃;
for 3h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetic acid / 100 °C / Inert atmosphere
2.1: N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 1 h / 20 °C / Sealed tube
2.2: 3 h / 80 °C / Sealed tube
2.3: 3 h / 60 °C
With
acetic acid; N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate;
In
N,N-dimethyl-formamide;
1.1: |Paal-Knorr Pyrrole Synthesis;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetic acid / 100 °C / Inert atmosphere
2.1: N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 1 h / 20 °C / Sealed tube
2.2: 3 h / 80 °C / Sealed tube
2.3: 3 h / 60 °C
With
acetic acid; N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate;
In
N,N-dimethyl-formamide;
1.1: |Paal-Knorr Pyrrole Synthesis;
