10H-Phenothiazin-2-amine

Base Information

Chemical Name:10H-Phenothiazin-2-amine
CAS No.:32338-15-1
Molecular Formula:C12H10 N2 S
Molecular Weight:214.29
Hs Code.:2934300000
DSSTox Substance ID:DTXSID60574070
Nikkaji Number:J806.752J
Wikidata:Q82462969
Mol file:32338-15-1.mol

Synonyms:10H-Phenothiazin-2-amine;32338-15-1;2-Aminophenothiazine;10H-phenothiazin-2-ylamine;SCHEMBL8318228;DTXSID60574070

Suppliers and Price of 10H-Phenothiazin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 10H-Phenothiazin-2-amine

Chemical Property:

Melting Point:187-189 °C
Boiling Point:443.8±34.0 °C(Predicted)
PKA:3.38±0.20(Predicted)
PSA：63.35000
Density:1.307±0.06 g/cm3(Predicted)
LogP:4.19620
XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:214.05646950
Heavy Atom Count:15
Complexity:234

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC3=C(S2)C=CC(=C3)N

Technology Process of 10H-Phenothiazin-2-amine

There total 5 articles about 10H-Phenothiazin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 92-39-7
2-chlorophenothiazine

: 32338-15-1
2-amino-10H-phenothiazine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; lithium hexamethyldisilazane; CyJohnPhos; In tetrahydrofuran; at 140 ℃; for 1h; regioselective reaction; Microwave irradiation; Inert atmosphere;
DOI:10.1002/ejoc.201300480

Reference yield: 83.0%

: 188798-67-6
phenothiazine-2-carbamic acid

: 32338-15-1
2-amino-10H-phenothiazine

Guidance literature:: With hydrogenchloride; water;
DOI:10.1080/004982597240703

Reference yield:

: 37711-29-8
Phenothiazine-2-carbamic acid ethyl ester

: 32338-15-1
2-amino-10H-phenothiazine

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / ethanol / 1.5 °C / Heating

2: 83 percent / HCl; H₂O

With hydrogenchloride; sodium hydroxide; water; In ethanol; 1: Hydrolysis / 2: Decarboxylation;
DOI:10.1080/004982597240703