2-((2-chloroethyl)aMino)ethanolHCLSALT

Base Information

• Chemical Name: 2-((2-chloroethyl)aMino)ethanolHCLSALT
• CAS No.: 2576-29-6
• Molecular Formula: C4H10 Cl N O . Cl H
• Molecular Weight: 123.5813
• Mol file: 2576-29-6.mol

Synonyms:Ethanol,2-[(2-chloroethyl)amino]-, hydrochloride (7CI,8CI,9CI);2-[(2-Chloroethyl)amino]ethanol hydrochloride

Chemical Property of 2-((2-chloroethyl)aMino)ethanolHCLSALT

Chemical Property:

• Vapor Pressure: 0.0127mmHg at 25°C
• Boiling Point: 230.2°Cat760mmHg
• Flash Point: 93°C
• PSA: 32.26000
• Density: 1.1g/cm³
• LogP: 1.00000
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

2-[(2-Chloroethyl)amino]ethanolHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-[(2-Chloroethyl)amino]ethanol is used to prepare phosphoramide mustard hydrolysis product.

Technology Process of 2-((2-chloroethyl)aMino)ethanolHCLSALT

There total 1 articles about 2-((2-chloroethyl)aMino)ethanolHCLSALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-[(2-chloroethyl)amino]ethanol hydrochloride (2576-29-6)

Guidance literature:

1-Aziridinaethanol, HCl, 30 min, 50grad;

Reference yield: 90.0%

di(tert-butyl) 2-[(2-chloro-3,5-dinitrobenzoyl)amino]ethyl phosphate (944088-64-6) + 2-[(2-chloroethyl)amino]ethanol hydrochloride (2576-29-6) → di(tert-butyl) 2-({2-[(2-chloroethyl)(2-hydroxyethyl)amino]-3,5-dinitrobenzoyl}amino)ethyl phosphate (944088-77-1)

Guidance literature:

With triethylamine; In 1,4-dioxane; at 20 ℃;

DOI:10.1016/j.tet.2007.04.044

Reference yield: 37.0%

2-chloro-3,5-dinitro-N-[2-(tetrahydro-2H-pyran-2-yloxy)ethyl]benzamide (680199-30-8) + 2-[(2-chloroethyl)amino]ethanol hydrochloride (2576-29-6) → 2-[(2-chloroethyl)(2-hydroxyethyl)amino]-3,5-dinitro-N-[2-(tetrahydro-2H-pyran-2-yloxy)ethyl]benzamide (944088-69-1)

Guidance literature:

With triethylamine; In 1,4-dioxane; at 20 ℃; Product distribution / selectivity;

Downstream raw materials:

2-[(2-chloroethyl)(2-hydroxyethyl)amino]-3,5-dinitro-N-[2-(tetrahydro-2H-pyran-2-yloxy)ethyl]benzamide

di(tert-butyl) 2-({2-[(2-chloroethyl)(2-hydroxyethyl)amino]-3,5-dinitrobenzoyl}amino)ethyl phosphate

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