(2E)-5-Hydroxy-2-hexensaeuremethylester

Base Information

• Chemical Name: (2E)-5-Hydroxy-2-hexensaeuremethylester
• CAS No.: 19870-59-8
• Molecular Formula: C₇H₁₂O₃
• Molecular Weight: 144.17
• Mol file: 19870-59-8.mol

Synonyms:(2E)-5-Hydroxy-2-hexensaeuremethylester

Chemical Property of (2E)-5-Hydroxy-2-hexensaeuremethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2E)-5-Hydroxy-2-hexensaeuremethylester

There total 1 articles about (2E)-5-Hydroxy-2-hexensaeuremethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + Grahamimycin A1 (74838-13-4,82467-16-1) → 3-hydroxybutyric acid methyl ester (1487-49-6) + (2E)-5-Hydroxy-2-hexensaeuremethylester (19870-59-8) + Dimethyl succinate (106-65-0)

Guidance literature:

With hydrogenchloride; sodium hydroxide; periodic acid; Multistep reaction; 1.) water:methanol 1:1; 1 h; overnight; 2.) dil. HCl;

DOI:10.1016/S0040-4039(00)71444-4

Reference yield: 38.0%

(2E)-5-Hydroxy-2-hexensaeuremethylester (19870-59-8) + (4R,5S)-4-benzyloxy-5-tert-butyldimethylsilyloxy-2(E)-hexenoic acid (294198-49-5) → (E)-(4R,5S)-4-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-hex-2-enoic acid (E)-4-methoxycarbonyl-1-methyl-but-3-enyl ester

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane;

DOI:10.1016/S0957-4166(02)00180-5

Reference yield:

(2E)-5-Hydroxy-2-hexensaeuremethylester (19870-59-8) → (2E,4E)-methylhexa-2,4-dienoate (689-89-4)

Guidance literature:

With sulfuric acid; In methanol; Heating;

DOI:10.1016/S0040-4039(00)71444-4

upstream raw materials:

diazomethane

Grahamimycin A₁

Downstream raw materials:

(2E,4E)-methylhexa-2,4-dienoate

trans-(+/-)-β-Benzyl-δ-methylvalerolactone

(E)-(S)-5-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-hex-2-enoic acid methyl ester

(S)-5-((R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionyloxy)-hexanoic acid methyl ester